DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fz3 and Sfrp2

DIOPT Version :9

Sequence 1:	NP_001096859.1	Gene:	fz3 / 31023	FlyBaseID:	FBgn0027343	Length:	646	Species:	Drosophila melanogaster
Sequence 2:	NP_001094170.1	Gene:	Sfrp2 / 310552	RGDID:	735163	Length:	295	Species:	Rattus norvegicus

Alignment Length:	142	Identity:	39/142 - (27%)
Similarity:	57/142 - (40%)	Gaps:	27/142 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   138 QIAKLVPLIESGCSRRARFLLCSSLFPLCTPDVPRPVAACKLLCETVRGECMENAPPELMEL--- 199
            |....:||:...|....:..|||...|:|..|:...:..|..||..|:..|   ||  :|..
  Rat    75 QAGAWIPLVMKQCHPDTKKFLCSLFAPVCLDDLDETIQPCHSLCVQVKDRC---AP--VMSAFGF 134

  Fly   200 -WPSFLNCDGLPQPEKHELCMQIPQEVAVPGGSPSG--PPTTGSPGVEDHPQTYRFWKSGASPTS 261
             ||..|.||..||  .::||        :|..|...  |||      |:.|:.....|:.....:
  Rat   135 PWPDMLECDRFPQ--DNDLC--------IPLASSDHLLPPT------EEAPKVCEACKTKNEDDN 183

  Fly   262 DLAGVLCPQNFS 273
            |:...||..:|:
  Rat   184 DIMETLCKNDFA 195

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fz3	NP_001096859.1	RRM	<19..>122	CDD:223796
		RRM_1	22..83	CDD:278504
		CRD_FZ	<138..224	CDD:295308	27/89 (30%)
		Frizzled	291..584	CDD:279827
Sfrp2	NP_001094170.1	CRD_SFRP2	36..163	CDD:143555	29/102 (28%)
Sfrp2	NP_001094170.1	NTR_Sfrp1_like	169..295	CDD:239635	6/27 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166334855
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3577
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740