DRSC/TRiP Functional Genomics Resources

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Protein Alignment fz3 and FRZB

DIOPT Version :10

Sequence 1:NP_001096859.1 Gene:fz3 / 31023 FlyBaseID:FBgn0027343 Length:646 Species:Drosophila melanogaster
Sequence 2:NP_001454.2 Gene:FRZB / 2487 HGNCID:3959 Length:325 Species:Homo sapiens


Alignment Length:91 Identity:28/91 - (30%)
Similarity:44/91 - (48%) Gaps:10/91 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly   145 LIESGCSRRARFLLCSSLFPLCTPDVP-RPVAACKLLCETVRGECMENAPPELMEL---WPSFLN 205
            |:.:.||....|.||:...|:||.|.. .|:..||.:||..|..|    .|.|::.   ||..|.
Human    75 LLGTHCSPDLLFFLCAMYAPICTIDFQHEPIKPCKSVCERARQGC----EPILIKYRHSWPENLA 135

  Fly   206 CDGLPQPEKHELCMQIPQEVAVPGGS 231
            |:.||..:: .:|:. |:.:....|:
Human   136 CEELPVYDR-GVCIS-PEAIVTADGA 159

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
fz3NP_001096859.1 RRM_1 22..83 CDD:425453
CRD_FZ <138..224 CDD:470581 27/82 (33%)
7tmF_FZD3_insect 290..587 CDD:320159
TM helix 1 299..324 CDD:320159
TM helix 2 333..354 CDD:320159
TM helix 3 383..409 CDD:320159
TM helix 4 426..442 CDD:320159
TM helix 5 469..493 CDD:320159
TM helix 6 513..540 CDD:320159
TM helix 7 548..573 CDD:320159
FRZBNP_001454.2 CRD_SFRP3 32..157 CDD:143550 27/87 (31%)
NTR_Sfrp3_like 188..297 CDD:239636
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 297..325
Blue background indicates that the domain is not in the aligned region.

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