DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fz3 and Cpz

DIOPT Version :9

Sequence 1:	NP_001096859.1	Gene:	fz3 / 31023	FlyBaseID:	FBgn0027343	Length:	646	Species:	Drosophila melanogaster
Sequence 2:	NP_694747.2	Gene:	Cpz / 242939	MGIID:	88487	Length:	654	Species:	Mus musculus

Alignment Length:	128	Identity:	40/128 - (31%)
Similarity:	55/128 - (42%)	Gaps:	15/128 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   145 LIESGCSRRARFLLCSSLFPLCT-PDVPRPVAACKLLCETVRGECMENAPPELMELWPSFLNCDG 208
            |:|..|:...|.|.||.|.|.|. ....||   |:.:||.:|..| :.|...:...||.||:|..
Mouse    93 LLEGQCNPDLRLLGCSVLAPRCEGGHTQRP---CRHVCEGLREAC-QPAFDAIDMAWPYFLDCAQ 153

  Fly   209 LPQPEK-------HELCMQIPQEVAVPGGSPSGPPTTGSPGVEDHPQTYRFWKSGASPTSDLA 264
            ...||:       .||..::..|.|:|.|.   |||........:.|..|..|..|:..|.:|
Mouse   154 YFAPEEEGCYDPLEELRGELDVEEALPSGL---PPTFIRFAHHSYAQMVRVLKRTAARCSQVA 213

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fz3	NP_001096859.1	RRM	<19..>122	CDD:223796
		RRM_1	22..83	CDD:278504
		CRD_FZ	<138..224	CDD:295308	27/86 (31%)
		Frizzled	291..584	CDD:279827
Cpz	NP_694747.2	CRD_FZ	45..172	CDD:295308	27/82 (33%)
		M14_CPZ	192..506	CDD:199849	6/22 (27%)
		Peptidase_M14NE-CP-C_like	510..586	CDD:200604
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	596..630
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000