| Sequence 1: | NP_001096859.1 | Gene: | fz3 / 31023 | FlyBaseID: | FBgn0027343 | Length: | 646 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_067432.2 | Gene: | Fzd1 / 14362 | MGIID: | 1196625 | Length: | 642 | Species: | Mus musculus |
| Alignment Length: | 517 | Identity: | 136/517 - (26%) |
|---|---|---|---|
| Similarity: | 213/517 - (41%) | Gaps: | 95/517 - (18%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 133 DDEKGQIAKLVPLIESGCSRRARFLLCSSLFPLCTPDVPRPVAACKLLCETVRGECMENAPPELM 197
Fly 198 E----LWPSFLNCDGLPQPEKHELCMQIPQEVAVPGGSPSGPPTTGSPGV-----EDHPQ----T 249
Fly 250 YRFWKSGASPTSDLAGVLCPQ----------NFSGSPFNPEECVPQCQRD-----AFHTSSQKKT 299
Fly 300 SETLILGLSAVCFVLTLFALVTFWAEPTRFGYPERPVLFLCLCYNLFSVCYLERIVFHNQARMHD 364
Fly 365 --VELQWRLMRPGCLLTPPCLASYITTSYLSLCAASWWLIFALCFYLSSHKKWSSEALEKRSGLF 427
Fly 428 HVLAWVPPLAPPIAALLLEKVRPSELTGMCYA--------PGFVELPALVLLLLGLYFTLRASRS 484
Fly 485 LLSLQQQLQPTLAHH------RFGQIRKRFVLFSLLYFAPTTAGV-----------------VAA 526
Fly 527 LCERYADSVPSCS-----TPDDCLSPTPLSAWPALVRIFFQLVGGTLTGLWVWSRKTCESYR 583 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| fz3 | NP_001096859.1 | RRM | <19..>122 | CDD:223796 | |
| RRM_1 | 22..83 | CDD:278504 | |||
| CRD_FZ | <138..224 | CDD:295308 | 27/89 (30%) | ||
| Frizzled | 291..584 | CDD:279827 | 90/331 (27%) | ||
| Fzd1 | NP_067432.2 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 26..45 | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 76..99 | ||||
| CRD_FZ1 | 107..233 | CDD:143574 | 31/106 (29%) | ||
| 7tmF_FZD1 | 294..641 | CDD:320375 | 91/342 (27%) | ||
| TM helix 1 | 313..338 | CDD:320375 | 9/24 (38%) | ||
| TM helix 2 | 347..368 | CDD:320375 | 9/20 (45%) | ||
| TM helix 3 | 398..424 | CDD:320375 | 5/25 (20%) | ||
| TM helix 4 | 441..457 | CDD:320375 | 6/15 (40%) | ||
| TM helix 5 | 479..508 | CDD:320375 | 9/28 (32%) | ||
| TM helix 6 | 528..555 | CDD:320375 | 7/26 (27%) | ||
| TM helix 7 | 591..616 | CDD:320375 | 5/27 (19%) | ||
| Lys-Thr-X-X-X-Trp motif, mediates interaction with the PDZ domain of Dvl family members. /evidence=ECO:0000250 | 620..625 | 2/4 (50%) | |||
| PDZ-binding | 640..642 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C167831136 | |
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG3577 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D167933at33208 | |
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 4 | 3.750 | |||||