| Sequence 1: | NP_001096859.1 | Gene: | fz3 / 31023 | FlyBaseID: | FBgn0027343 | Length: | 646 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_009128.1 | Gene: | FZD10 / 11211 | HGNCID: | 4039 | Length: | 581 | Species: | Homo sapiens |
| Alignment Length: | 550 | Identity: | 151/550 - (27%) |
|---|---|---|---|
| Similarity: | 238/550 - (43%) | Gaps: | 123/550 - (22%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 138 QIAKLVPLIESGCSRRARFLLCSSLFPLCTPDVPRPVAACKLLCETVRGECMENAPPELME---- 198
Fly 199 LWPSFLNCDGLP-QPEKHELCMQIPQEVAVPGGSPSGPPTTGS------------PGVEDHPQTY 250
Fly 251 RFWKSGASPTSDLAGVLCPQNFSGSPFNP---------EECVPQCQR--DAFHTSSQKKTSETLI 304
Fly 305 LGLSAVCFVLTLFALVTFWAEPTRFGYPERPVLFLCLCYNLFSVCYLERIVFHNQARMHDVE--- 366
Fly 367 ---LQWRLMRPGCLLTPPCLASYITTSYLSLCAASWWLIFALCFYLSSHKKWSSEALEKRSGLFH 428
Fly 429 VLAWVPPLAPPIAALLLEKVRPSELTGMCYA--------PGFVELPALVLLLLGLYFTLRASRSL 485
Fly 486 LSLQQQLQPTLAH-HRFGQIRKRFVLFSLLYFAPTTAGVVAALCER-------YADSVPSCSTPD 542
Fly 543 -----DCLSPTPLSAWPA----LVRIFFQLVGGTLTGLWVWSRKTCESYR----NRLGASGTPTS 594
Fly 595 SLMNQSKAAGALPKKHLYTSGKSMLPTGGI 624 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| fz3 | NP_001096859.1 | RRM | <19..>122 | CDD:223796 | |
| RRM_1 | 22..83 | CDD:278504 | |||
| CRD_FZ | <138..224 | CDD:295308 | 35/90 (39%) | ||
| Frizzled | 291..584 | CDD:279827 | 92/327 (28%) | ||
| FZD10 | NP_009128.1 | CRD_FZ10 | 30..156 | CDD:143571 | 35/100 (35%) |
| 7tmF_FZD10 | 217..535 | CDD:320165 | 92/326 (28%) | ||
| TM helix 1 | 226..251 | CDD:320165 | 5/24 (21%) | ||
| TM helix 2 | 260..281 | CDD:320165 | 11/20 (55%) | ||
| TM helix 3 | 310..336 | CDD:320165 | 5/31 (16%) | ||
| TM helix 4 | 353..369 | CDD:320165 | 6/15 (40%) | ||
| TM helix 5 | 391..420 | CDD:320165 | 8/28 (29%) | ||
| TM helix 6 | 440..467 | CDD:320165 | 9/26 (35%) | ||
| TM helix 7 | 497..522 | CDD:320165 | 9/27 (33%) | ||
| Lys-Thr-X-X-X-Trp motif, mediates interaction with the PDZ domain of Dvl family members. /evidence=ECO:0000250 | 526..531 | 2/4 (50%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 560..581 | ||||
| PDZ-binding | 579..581 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C165141185 | |
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG3577 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D509772at2759 | |
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 1 | 1.100 | - | - | O | PTHR11309 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 5 | 4.850 | |||||