Protein Alignment CG5254 and SLC25A21

DIOPT Version :10

• Sequence 1: NP_569856.2
• Gene: CG5254 / 31020
• FlyBaseID: FBgn0040383
• Length: 306
• Species: Drosophila melanogaster
• Sequence 2: NP_085134.1
• Gene: SLC25A21 / 89874
• HGNCID: 14411
• Length: 299
• Species: Homo sapiens
• Alignment Length: 303
• Identity: 175/303 - (57%)
• Similarity: 226/303 - (74%)
• Gaps: 13/303 - (4%)

  Fly     7 DISHAKRAAFQVLAGGSAGFLEVCIMQPLDVVKTRIQIQ--ATPAPNAAALGEVHYNGVFDCFAK 69
            ::|..:.|:.|::||||||.:|:|:|.||||||||.|||  ||. ||:       |..:.|.|..
Human     6 EVSLVREASRQIVAGGSAGLVEICLMHPLDVVKTRFQIQRCATD-PNS-------YKSLVDSFRM 62

  Fly    70 MYRHEGISSYWKGIMPPILAETPKRAIKFLVFEQTKPLFQFGSPTPTPLTFSLAGLTAGTLEAIA 134
            :::.||:..::|||:|||||||||||:||..|||.|.|..:.|.:|. |||::|||.:|..|||.
Human    63 IFQMEGLFGFYKGILPPILAETPKRAVKFFTFEQYKKLLGYVSLSPA-LTFAIAGLGSGLTEAIV 126

  Fly   135 VNPFEVVKVAQQADRQ--KKMLSTFAVAKGIIQQDGLGFSGLNKGITATMGRNGVFNMVYFGFYH 197
            |||||||||..||:|.  .:..||...|:.||:::|.|..|||||:|||:||:|||||||||||:
Human   127 VNPFEVVKVGLQANRNTFAEQPSTVGYARQIIKKEGWGLQGLNKGLTATLGRHGVFNMVYFGFYY 191

  Fly   198 SVKNVVPEYKESHLEFLRKVTIGFLAGTLACFVNIPFDVAKSRIQGPQPVPGQIKYRGTLSSMGI 262
            :|||::|..|:..|||.||..||.|:||:|..:|||||||||||||||||||:||||....:|..
Human   192 NVKNMIPVNKDPILEFWRKFGIGLLSGTIASVINIPFDVAKSRIQGPQPVPGEIKYRTCFKTMAT 256

  Fly   263 VYREEGFRALYKGLVPKIMRLGPGGAILLLVFEYSYDYLLHNY 305
            ||:|||..||||||:|||||||||||::|||:||:|.:|..|:
Human   257 VYQEEGILALYKGLLPKIMRLGPGGAVMLLVYEYTYSWLQENW 299

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5254	NP_569856.2	Mito_carr	18..112	CDD:395101	50/95 (53%)
		Mito_carr	122..207	CDD:395101	51/86 (59%)
		Mito_carr	209..305	CDD:395101	64/95 (67%)
SLC25A21	NP_085134.1	Solcar 1	11..100		51/96 (53%)
		Mito_carr	15..105	CDD:395101	51/97 (53%)
		Mito_carr	105..197	CDD:395101	55/92 (60%)
		Solcar 2	107..196		53/89 (60%)
		Mito_carr	205..298	CDD:395101	64/92 (70%)
		Solcar 3	205..294		63/88 (72%)