DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5254 and ODC1

DIOPT Version :9

Sequence 1:	NP_569856.2	Gene:	CG5254 / 31020	FlyBaseID:	FBgn0040383	Length:	306	Species:	Drosophila melanogaster
Sequence 2:	NP_015191.1	Gene:	ODC1 / 855969	SGDID:	S000006055	Length:	310	Species:	Saccharomyces cerevisiae

Alignment Length:	296	Identity:	124/296 - (41%)
Similarity:	169/296 - (57%)	Gaps:	19/296 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 FQVLAGGSAGFLEVCIMQPLDVVKTRIQIQAT----PAPNAAALGEVHYNGVFDCFAKMYRHEGI 76
            :|..||..||..|:.:|.||||||||:|:|.|    ||..||.....||.||.||..|:.:.||.
Yeast    13 YQFTAGAIAGVSELLVMYPLDVVKTRMQLQVTTKGHPAVVAAKAAVDHYTGVMDCLTKIVKKEGF 77

  Fly    77 SSYWKGIMPPILAETPKRAIKFLVFEQTKPLFQFGSPTPT-PLTFSLA---GLTAGTLEAIAVNP 137
            |..:|||..|||.|.|||||||...:..:..::...|||. .:|..:|   |.:||.:||..|.|
Yeast    78 SHLYKGITSPILMEAPKRAIKFSGNDTFQTFYKKIFPTPNGEMTQKIAIYSGASAGAVEAFVVAP 142

  Fly   138 FEVVKVAQQADRQKKMLSTFAVAKGIIQQDGLGFSGLNKGITATMGRNGVFNMVYFGFYHSVKNV 202
            ||:||:..| |...:..:...|.|..:.:.|:  ..|..|:.||:.|:.::|..|||....::.:
Yeast   143 FELVKIRLQ-DVNSQFKTPIEVVKNSVVKGGV--LSLFNGLEATIWRHVLWNAGYFGIIFQIRKL 204

  Fly   203 VPEYKESHLEFLRKVTIGFLAGTLACFVNIPFDVAKSRIQ---GPQPVPGQIKYRGTLSSMGIVY 264
            :|..|.|..:....:..|.:.||:.|.:|.||||.|||||   ||..     ||..:|.|:.:||
Yeast   205 LPAAKTSTEKTRNDLIAGAIGGTVGCLLNTPFDVVKSRIQRSSGPLR-----KYNWSLPSVLLVY 264

  Fly   265 REEGFRALYKGLVPKIMRLGPGGAILLLVFEYSYDY 300
            |||||:|||||..||:|||.|||.:||:||....|:
Yeast   265 REEGFKALYKGFAPKVMRLAPGGGLLLVVFTNVMDF 300

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5254	NP_569856.2	Mito_carr	18..112	CDD:278578	45/97 (46%)
		PTZ00169	19..301	CDD:240302	123/293 (42%)
		Mito_carr	122..207	CDD:278578	27/87 (31%)
		Mito_carr	209..305	CDD:278578	46/95 (48%)
ODC1	NP_015191.1	Mito_carr	8..113	CDD:395101	46/99 (46%)
ODC1	NP_015191.1	PTZ00169	11..302	CDD:240302	124/296 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157346473
Domainoid	1	1.000	87	1.000	Domainoid score	I1835
eggNOG	1	0.900	-	-		E1_KOG0754
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	210	1.000	Inparanoid score	I810
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53612
OrthoFinder	1	1.000	-	-		FOG0004440
OrthoInspector	1	1.000	-	-		mtm9243
orthoMCL	1	0.900	-	-		OOG6_101369
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R860
SonicParanoid	1	1.000	-	-		X2643
TreeFam	1	0.960	-	-
	13	12.690