Protein Alignment CG5254 and SLC25A1

DIOPT Version :10

• Sequence 1: NP_569856.2
• Gene: CG5254 / 31020
• FlyBaseID: FBgn0040383
• Length: 306
• Species: Drosophila melanogaster
• Sequence 2: NP_001243463.1
• Gene: SLC25A1 / 6576
• HGNCID: 10979
• Length: 318
• Species: Homo sapiens
• Alignment Length: 305
• Identity: 88/305 - (28%)
• Similarity: 139/305 - (45%)
• Gaps: 52/305 - (17%)

  Fly    13 RAAFQVLAGGSAGFLEVCIMQPLDVVKTRIQIQATPAPNAAALGEVHYNGVFDCFAKMYRHEGIS 77
            |:.|.|.|||.||.:|:||..|.:.|||::|:.....|       ..|.|:.||..:..|..|:.
Human    31 RSGFPVPAGGLAGGIEICITFPTEYVKTQLQLDERSHP-------PRYRGIGDCVRQTVRSHGVL 88

  Fly    78 SYWKGIMPPILAETPKRAIKFLVFE--------------QTKPLFQFGSPTPTPLTFSLAGLTAG 128
            ..::|:...:....||.|::|.:||              .|:.|              |.||.||
Human    89 GLYRGLSSLLYGSIPKAAVRFGMFEFLSNHMRDAQGRLDSTRGL--------------LCGLGAG 139

  Fly   129 TLEA-IAVNPFEVVKVA---QQADRQKKMLSTFAVAKGIIQQDGLGFSGLNKGITATMGRNGVFN 189
            ..|| :.|.|.|.:||.   .|.....|....|...:.|:::.||  .|..:|:|||:.:.|...
Human   140 VAEAVVVVCPMETIKVKFIHDQTSPNPKYRGFFHGVREIVREQGL--KGTYQGLTATVLKQGSNQ 202

  Fly   190 MVYFGFYHSVKNVVPEYKESH----LEFLRKVTIGFLAGTLACFVNIPFDVAKSRIQGPQPVPGQ 250
            .:.|....|::|   .|:..:    :..|.....|.:||..:.|.|.|.||.|:|:||.:    .
Human   203 AIRFFVMTSLRN---WYRGDNPNKPMNPLITGVFGAIAGAASVFGNTPLDVIKTRMQGLE----A 260

  Fly   251 IKYRGTLSSMGIVYREEGFRALYKGLVPKIMRLGPGGAILLLVFE 295
            .|||.|......:.::||.:|.|||.||::.|:....||:.::::
Human   261 HKYRNTWDCGLQILKKEGLKAFYKGTVPRLGRVCLDVAIVFVIYD 305

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5254	NP_569856.2	Mito_carr	18..112	CDD:395101	30/107 (28%)
		Mito_carr	122..207	CDD:395101	27/88 (31%)
		Mito_carr	209..305	CDD:395101	28/91 (31%)
SLC25A1	NP_001243463.1	Mito_carr	38..121	CDD:395101	27/89 (30%)
		Mito_carr	<148..220	CDD:395101	20/76 (26%)
		Mito_carr	223..313	CDD:395101	28/87 (32%)