DRSC/TRiP Functional Genomics Resources

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Protein Alignment sdk and Kirrel3

DIOPT Version :9

Sequence 1:NP_001284756.1 Gene:sdk / 31017 FlyBaseID:FBgn0021764 Length:2265 Species:Drosophila melanogaster
Sequence 2:XP_006510620.1 Gene:Kirrel3 / 67703 MGIID:1914953 Length:803 Species:Mus musculus


Alignment Length:541 Identity:127/541 - (23%)
Similarity:192/541 - (35%) Gaps:146/541 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly   228 GYRAKAINTQLGKEESSAFVHLNVSGDPYIEVAPEIIVRPQDVKVKVGTGVVELQCIANARPLHE 292
            ||.||           ..|..:| .|..|     ....:||| :|.|....|.|.|   |.|.::
Mouse    32 GYMAK-----------DKFRRMN-EGQVY-----SFSQQPQD-QVVVSGQPVTLLC---AIPEYD 75

  Fly   293 LETLWLKDGLAVETAGVRHTLND-----------PWNRTLALLQANSSHSGEYTCQVRLRSGGYP 346
            ...||:|||||:   ||...|:.           .....|.:|:|.......|.||         
Mouse    76 GFVLWIKDGLAL---GVGRDLSSYPQYLVVGNHLSGEHHLKILRAELQDDAVYECQ--------- 128

  Fly   347 AVSAS-----ARLQILEPP----LFFTP---MRAETFGEFGGQVQLTCDV-VGEPTPQVKWFRNA 398
            |:.|:     |||.:|.||    :...|   :||      |..:.|||.. ..:|...:.|.|..
Mouse   129 AIQAAIRSRPARLTVLVPPDDPIILGGPVISLRA------GDPLNLTCHADNAKPAASIIWLRKG 187

  Fly   399 ESVDAHIESGRYTLNTD-------NTLVIKKLILDDAAMFQCLAINEA--GENSASTWLRVKTKT 454
            |.::....|  .||..|       :||.|....:::.....|.|.|:|  |....|..:.::...
Mouse   188 EVINGATYS--KTLLRDGKRESIVSTLFISPGDVENGQSIVCRATNKAIPGGKETSVTIDIQHPP 250

  Fly   455 AKN----------------RVKRLAQPRILRVRASHAG-----------------------LGSE 480
            ..|                .....|.|.:.:.|.:..|                       :..|
Mouse   251 LVNLSVEPQPVLEDNIVTFHCSAKANPAVTQYRWAKRGHIIKEASGELYRTTVDYTYFSEPVSCE 315

  Fly   481 KGSESGSSDRRKEFRFASAPIMELPPQNVTALDGKDATISCRAVGSPNPNITWIYNETQLVDISS 545
            ..:..||::..:.......|.|...||::....|.||..||..:|:|:..|.|:..       .|
Mouse   316 VTNALGSTNLSRTVDVYFGPRMTSEPQSLLVDLGSDAVFSCAWIGNPSLTIVWMKR-------GS 373

  Fly   546 RVQILESGDLLISNIRSVDAGLYICVRANEAGSVKGEAYLSVLVRTQIIQPPVDTT-----VLLG 605
            .|.:.....|.:.::|..|||.|:| ||.......||..:::.|.    .||:.::     .|.|
Mouse   374 GVVLSNEKTLTLKSVRQEDAGKYVC-RAVVPRVGAGEREVTLTVN----GPPIISSTQTQHALHG 433

  Fly   606 LTATLQCKVSSDPSVPYNIDW-YREG--QSSTPISNSQRIGVQA----DGQLEI----QAVRASD 659
            ....::|.:.|.|. |..|.| ::|.  :|.|    |.|..|:.    :|.:..    ..|||..
Mouse   434 EKGQIKCFIRSTPP-PDRIAWSWKENVLESGT----SGRYTVETVNTEEGVISTLTISNIVRADF 493

  Fly   660 VGSYACVVTSPGGNETRAARL 680
            ...|.|...:..|::|...||
Mouse   494 QTIYNCTAWNSFGSDTEIIRL 514

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
sdkNP_001284756.1 Ig 71..157 CDD:299845
I-set 72..150 CDD:254352
Ig 172..245 CDD:299845 4/16 (25%)
IG_like 280..356 CDD:214653 25/91 (27%)
Ig 280..343 CDD:299845 20/73 (27%)
IG_like 375..450 CDD:214653 21/84 (25%)
Ig 378..447 CDD:143165 20/78 (26%)
Ig 506..587 CDD:299845 24/80 (30%)
IG_like 506..587 CDD:214653 24/80 (30%)
I-set 592..682 CDD:254352 26/105 (25%)
Ig 595..682 CDD:299845 26/102 (25%)
FN3 686..789 CDD:238020
FN3 798..893 CDD:238020
FN3 901..1005 CDD:238020
fn3 1011..1094 CDD:278470
FN3 1108..1202 CDD:238020
FN3 1210..1308 CDD:238020
fn3 1317..1402 CDD:278470
FN3 1415..1507 CDD:238020
FN3 1513..1608 CDD:238020
fn3 1617..1708 CDD:278470
FN3 1722..1823 CDD:238020
FN3 1828..1920 CDD:238020
FN3 1927..2016 CDD:238020
Kirrel3XP_006510620.1 IG_like 54..143 CDD:214653 31/104 (30%)
Ig strand A' 56..60 CDD:409353 2/4 (50%)
Ig strand B 64..71 CDD:409353 3/9 (33%)
Ig strand C 78..82 CDD:409353 2/3 (67%)
Ig strand C' 84..87 CDD:409353 2/2 (100%)
Ig strand D 97..101 CDD:409353 0/3 (0%)
Ig strand E 104..116 CDD:409353 1/11 (9%)
Ig strand G 132..143 CDD:409353 4/10 (40%)
IgI_2_KIRREL3-like 149..246 CDD:409416 24/104 (23%)
Ig strand B 166..170 CDD:409416 1/3 (33%)
Ig strand C 180..184 CDD:409416 0/3 (0%)
Ig strand E 210..214 CDD:409416 2/3 (67%)
Ig strand F 224..229 CDD:409416 1/4 (25%)
Ig strand G 239..242 CDD:409416 0/2 (0%)
Ig <267..334 CDD:416386 7/66 (11%)
Ig strand B 267..274 CDD:409353 0/6 (0%)
Ig strand C 279..286 CDD:409353 1/6 (17%)
Ig strand C' 288..291 CDD:409353 1/2 (50%)
Ig strand D 298..302 CDD:409353 0/3 (0%)
Ig strand E 304..310 CDD:409353 0/5 (0%)
Ig strand G 321..334 CDD:409353 2/12 (17%)
Ig 335..416 CDD:416386 26/88 (30%)
Ig strand A' 343..347 CDD:409353 0/3 (0%)
Ig strand B 350..360 CDD:409353 4/9 (44%)
Ig strand C 365..371 CDD:409353 2/5 (40%)
Ig strand E 381..387 CDD:409353 1/5 (20%)
IgI_5_KIRREL3 418..515 CDD:409479 26/102 (25%)
Ig strand B 436..440 CDD:409479 0/3 (0%)
Ig strand C 450..454 CDD:409479 1/3 (33%)
Ig strand E 481..485 CDD:409479 0/3 (0%)
Ig strand F 496..501 CDD:409479 2/4 (50%)
Ig strand G 509..512 CDD:409479 1/2 (50%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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