DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment sdk and opcml

DIOPT Version :9

Sequence 1:NP_001284756.1 Gene:sdk / 31017 FlyBaseID:FBgn0021764 Length:2265 Species:Drosophila melanogaster
Sequence 2:NP_001005580.1 Gene:opcml / 449538 ZFINID:ZDB-GENE-040927-3 Length:342 Species:Danio rerio


Alignment Length:303 Identity:63/303 - (20%)
Similarity:116/303 - (38%) Gaps:62/303 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   398 AESVDAHIESGRYTLNTDNTLVIKKLILDDAAMFQCLAINEAGENSASTWLRVKTKTAKNRVKRL 462
            |.|.|::::        ||..|.:    .|:|:.:|...|:.   |...||...|.......|..
Zfish    31 ARSGDSYLK--------DNITVRQ----GDSAVLKCSMDNKV---SRVAWLNRTTILFTGNEKWS 80

  Fly   463 AQPRIL---------RVRASHAGLGSEKGSESGSSDRRKEFRFASAPIMELPPQ------NVTAL 512
            ..||::         .::..:..|..|..........:|........|:::|.:      :|:..
Zfish    81 LDPRVVLLNTAVNEYSIKILNVNLYDEGPYVCSILTNKKPESTKVHLIVQVPARIVNVSTDVSVN 145

  Fly   513 DGKDATISCRAVGSPNPNITWIYNETQLVDISSRVQILESGDLLISNIRSVDAGLYICVRANEAG 577
            :|.:.::.|.|:|.|.|:|.|.:..::    .:|: :.|...:.::.|....:|.|.|:.:|:..
Zfish   146 EGSNVSLMCLAIGRPEPSILWKFRSSK----GNRI-VTEGEYVEMTGITKDMSGSYDCITSNDIS 205

  Fly   578 --SVKGEAYLSVLVRTQIIQPPV-----DTTVLLGLTATLQCKVSSDPSVPYNIDWYR------E 629
              .|:       .|:..:..|||     .|...:|....|.|:.|:.|...:  .|::      .
Zfish   206 PPDVR-------TVQVTVNYPPVISRARSTGTAVGQKGVLWCEASAVPLADF--QWFKGERRILN 261

  Fly   630 GQSSTPISNSQRIGVQADGQLEIQAVRASDVGSYACVVTSPGG 672
            |.:...|.|.   |.|:  .|....|...|.|:|.||..:..|
Zfish   262 GFNGVKIENK---GKQS--MLTFFNVSEEDYGNYTCVAINTLG 299

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
sdkNP_001284756.1 Ig 71..157 CDD:299845
I-set 72..150 CDD:254352
Ig 172..245 CDD:299845
IG_like 280..356 CDD:214653
Ig 280..343 CDD:299845
IG_like 375..450 CDD:214653 13/51 (25%)
Ig 378..447 CDD:143165 11/48 (23%)
Ig 506..587 CDD:299845 17/88 (19%)
IG_like 506..587 CDD:214653 17/88 (19%)
I-set 592..682 CDD:254352 23/92 (25%)
Ig 595..682 CDD:299845 23/89 (26%)
FN3 686..789 CDD:238020
FN3 798..893 CDD:238020
FN3 901..1005 CDD:238020
fn3 1011..1094 CDD:278470
FN3 1108..1202 CDD:238020
FN3 1210..1308 CDD:238020
fn3 1317..1402 CDD:278470
FN3 1415..1507 CDD:238020
FN3 1513..1608 CDD:238020
fn3 1617..1708 CDD:278470
FN3 1722..1823 CDD:238020
FN3 1828..1920 CDD:238020
FN3 1927..2016 CDD:238020
opcmlNP_001005580.1 Ig 41..129 CDD:299845 16/94 (17%)
IG_like 41..129 CDD:214653 16/94 (17%)
IG_like 139..216 CDD:214653 18/88 (20%)
IGc2 146..202 CDD:197706 14/60 (23%)
I-set 219..307 CDD:254352 23/88 (26%)
ig 223..307 CDD:278476 20/84 (24%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.900

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