DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sdk and dpr16

DIOPT Version :9

Sequence 1:	NP_001284756.1	Gene:	sdk / 31017	FlyBaseID:	FBgn0021764	Length:	2265	Species:	Drosophila melanogaster
Sequence 2:	NP_001287169.1	Gene:	dpr16 / 40619	FlyBaseID:	FBgn0037295	Length:	488	Species:	Drosophila melanogaster

Alignment Length:	328	Identity:	66/328 - (20%)
Similarity:	102/328 - (31%)	Gaps:	106/328 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   465 PRILRVRASHAGLGSEKG--------------------SESGSSDRRKEFRFAS------APIME 503
            |.:||..:|.|...::.|                    ||..:...|:|...|.      ...:.
  Fly   138 PHMLRNASSGAAPPADIGPSGSPMPSKPNEQSRLHAYDSEQKAQQLRREKELAKERELLPRRQLS 202

  Fly   504 LPPQNVTALDGKDATISCRAVGSPNPNITWI---------------YNETQLVDI--SSRVQILE 551
            |||.|.|...|:.|.:.|:........::|:               .|:.:...:  |:.:..|.
  Fly   203 LPPLNATVQAGQHAYLPCKLNQHSGKPLSWVRLRDEHIIAVDHTTFINDARFASLLQSTTLTTLV 267

  Fly   552 SGDLL-----------------------------------ISNIRSVDAGLYICVRANEAG-SVK 580
            ||..|                                   |..:...|||.|.|..|.|.. |.|
  Fly   268 SGGALSTTATPVAALGNSFAHAVPGGQERGNSSSLSWTLQIKYVNLEDAGWYECQLATEPKMSAK 332

  Fly   581 GEAYLSVLVRTQIIQPPVDTTVLLGLTATLQCKVSSDPSVPYNIDWYREGQSSTPISNSQRIGVQ 645
            .:.:: :..||::|... ...|..|....|.|.|......|..|.|||..|..|  :.::..|.|
  Fly   333 VQLFV-ITPRTELIGDR-QRFVKAGSRVELHCIVRGTLEAPKYIFWYRGDQQVT--AENEASGAQ 393

  Fly   646 AD--------------------GQLEIQAVRASDVGSYACVVTSPGGNETRAARLSVIELPFPPS 690
            :.                    |.|.|..||....|:|.|   .|..:...:.:|.|:...:..|
  Fly   394 SGWYTQIDRNIFGSTEHNRNTIGSLVIPLVRKIHSGNYTC---EPENSAAASMQLHVLSGEYSAS 455

  Fly   691 NVK 693
            .:|
  Fly   456 AIK 458

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sdk	NP_001284756.1	Ig	71..157	CDD:299845
		I-set	72..150	CDD:254352
		Ig	172..245	CDD:299845
		IG_like	280..356	CDD:214653
		Ig	280..343	CDD:299845
		IG_like	375..450	CDD:214653
		Ig	378..447	CDD:143165
		Ig	506..587	CDD:299845	23/133 (17%)
		IG_like	506..587	CDD:214653	23/133 (17%)
		I-set	592..682	CDD:254352	25/109 (23%)
		Ig	595..682	CDD:299845	24/106 (23%)
		FN3	686..789	CDD:238020	2/8 (25%)
		FN3	798..893	CDD:238020
		FN3	901..1005	CDD:238020
		fn3	1011..1094	CDD:278470
		FN3	1108..1202	CDD:238020
		FN3	1210..1308	CDD:238020
		fn3	1317..1402	CDD:278470
		FN3	1415..1507	CDD:238020
		FN3	1513..1608	CDD:238020
		fn3	1617..1708	CDD:278470
		FN3	1722..1823	CDD:238020
		FN3	1828..1920	CDD:238020
		FN3	1927..2016	CDD:238020
dpr16	NP_001287169.1	IG_like	205..337	CDD:214653	23/131 (18%)
		Ig	<298..338	CDD:299845	10/40 (25%)
		IG_like	352..447	CDD:214653	24/99 (24%)
		Ig	358..439	CDD:143165	21/85 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810