DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sdk and dpr10

DIOPT Version :9

Sequence 1:	NP_001284756.1	Gene:	sdk / 31017	FlyBaseID:	FBgn0021764	Length:	2265	Species:	Drosophila melanogaster
Sequence 2:	NP_729591.1	Gene:	dpr10 / 39180	FlyBaseID:	FBgn0052057	Length:	408	Species:	Drosophila melanogaster

Alignment Length:	291	Identity:	56/291 - (19%)
Similarity:	98/291 - (33%)	Gaps:	97/291 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   480 EKGSESGSSDRRKEFRFASAPIMELP--------------PQNVTALDGKDATISCRAVGSPNPN 530
            ::.|.|.::....|.:...||....|              |:|:|:|.||.|.:.||.....|..
  Fly    20 QRQSVSNNNHNNAEAKPTHAPPSHYPHGHKWNEPYFDLTMPRNITSLVGKSAYLGCRVKHLGNKT 84

  Fly   531 ITWI-YNETQLVDISS-------RVQI-----LESGDLLISNIRSVDAGLYIC-----------V 571
            :.|| :.:..::.:.:       |.|.     ::...|.|...:..|||:|.|           |
  Fly    85 VAWIRHRDLHILTVGTYTYTTDQRFQTSYHRDIDEWTLQIKWAQQRDAGVYECQISTQPVRSYSV 149

  Fly   572 RAN-------EAGSVKGEAY---------------------------LSVLVRTQIIQPPVDTTV 602
            ..|       |...:..:.|                           .:|.|.|..|....|..|
  Fly   150 NLNIVDLIDAETSDIMQQYYNDDAFYIAENRVYQSSNDEFAGMFGPIQTVAVPTATILGGPDLYV 214

  Fly   603 LLGLTATLQCKVSSDPSVPYNIDWYREGQSSTPISNSQRIGVQADGQLEIQAVRASDV------- 660
            ..|.|..|.|.:...|..|.:|.||.:.:    :.:.:..|    |:|:.:.:::.:.
  Fly   215 DKGSTINLTCIIKFSPEPPTHIFWYHQDK----VLSEETSG----GRLKFKTIKSEETKSILLIY 271

  Fly   661 -------GSYACVVTSPGGNETRAARLSVIE 684
                   |.|:|.   |...|..:.|:.|::
  Fly   272 DADLLHSGKYSCY---PSNTEIASIRVHVLQ 299

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sdk	NP_001284756.1	Ig	71..157	CDD:299845
		I-set	72..150	CDD:254352
		Ig	172..245	CDD:299845
		IG_like	280..356	CDD:214653
		Ig	280..343	CDD:299845
		IG_like	375..450	CDD:214653
		Ig	378..447	CDD:143165
		Ig	506..587	CDD:299845	25/138 (18%)
		IG_like	506..587	CDD:214653	25/138 (18%)
		I-set	592..682	CDD:254352	21/103 (20%)
		Ig	595..682	CDD:299845	20/100 (20%)
		FN3	686..789	CDD:238020
		FN3	798..893	CDD:238020
		FN3	901..1005	CDD:238020
		fn3	1011..1094	CDD:278470
		FN3	1108..1202	CDD:238020
		FN3	1210..1308	CDD:238020
		fn3	1317..1402	CDD:278470
		FN3	1415..1507	CDD:238020
		FN3	1513..1608	CDD:238020
		fn3	1617..1708	CDD:278470
		FN3	1722..1823	CDD:238020
		FN3	1828..1920	CDD:238020
		FN3	1927..2016	CDD:238020
dpr10	NP_729591.1	Ig	63..143	CDD:299845	19/79 (24%)
		IG_like	210..297	CDD:214653	20/97 (21%)
		IGc2	217..287	CDD:197706	16/80 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810