| Sequence 1: | NP_001284756.1 | Gene: | sdk / 31017 | FlyBaseID: | FBgn0021764 | Length: | 2265 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_002175.2 | Gene: | IL6ST / 3572 | HGNCID: | 6021 | Length: | 918 | Species: | Homo sapiens |
| Alignment Length: | 988 | Identity: | 192/988 - (19%) |
|---|---|---|---|
| Similarity: | 333/988 - (33%) | Gaps: | 303/988 - (30%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 800 PVGFVGSARSMSEIITQWQPPLEEHRNGQILGYILRYRLFGY-----NNVPWSYQNITNEAQRNF 859
Fly 860 LIQEL---ITWKDYIVQIAAYN-NMGVGVYTEGS------KIKTKEGVPEAPPTNVKVEAINSTA 914
Fly 915 ARCRWTPPNPQQINGINQGYKIQAWQRRLIDGEW-----RDIERRMKTVPPSLIDPLAEQTAILG 974
Fly 975 GLEKFTEYNISVLCFTDPGDGVASSQVAVMTMDDV------------PDEVTGLHFDDVSDRSVK 1027
Fly 1028 VLWAPPRASNGILTGYTVRYQVKDRPDTLKSFNLTADDT-----ELTVNQLQATTHYWFEIVA-- 1085
Fly 1086 ---------WTRVGSGI------PKTATIQSGVEPVLPHAPTALALSNIEAF---SVVLQFTPGF 1132
Fly 1133 DGNSSI-------TKWK--VEGQTARNMTWFTICEINDPDAETLTVTGLVPFTQYRLRLSASNVV 1188
Fly 1189 GSSKPS---------EATKDFQTIQARPKHPPFNVTVRAMSAQQLRVRWIPLQQTEWYGNPRGYN 1244
Fly 1245 ISYKQLVKTPGTIKYVPRSVVI------------EDHTAN-SHVLDSLEEWTLYEVKMN-ACNDV 1295
Fly 1296 GCSKESDTAVERTREAVPSYGPLDVQANATSSTTVVVQWGEVPRQHRNGQIDGYKVFYAAADRGQ 1360
Fly 1361 QVLHKTIPNNATFTT--------TLTELKKYVVYHVQVLAYTRLGNGALSTPPIRVQTFEDTPG- 1416
Fly 1417 -----VPSNVSFPDVSL-----------TMARIIWDVPVDPNGKILAYQVTYT-----LNGSAML 1460
Fly 1461 ----------------NYSREFPPSDRT---FRATELLPGKYYS----FSCTAQTRLGWG----- 1497
Fly 1498 ----KIATALVYTT--NNRERPQAPSVPQISRSQIQAHQITFSWTP----------GRDGFAPLR 1546
Fly 1547 YYTVEMRENEGRWQPLPERVDPSLSSF------TAVGLRPYMTYQFRIQATNDLGPSAFSRESVI 1605
Fly 1606 VRTLPAAPAVGVG 1618 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| sdk | NP_001284756.1 | Ig | 71..157 | CDD:299845 | |
| I-set | 72..150 | CDD:254352 | |||
| Ig | 172..245 | CDD:299845 | |||
| IG_like | 280..356 | CDD:214653 | |||
| Ig | 280..343 | CDD:299845 | |||
| IG_like | 375..450 | CDD:214653 | |||
| Ig | 378..447 | CDD:143165 | |||
| Ig | 506..587 | CDD:299845 | |||
| IG_like | 506..587 | CDD:214653 | |||
| I-set | 592..682 | CDD:254352 | |||
| Ig | 595..682 | CDD:299845 | |||
| FN3 | 686..789 | CDD:238020 | |||
| FN3 | 798..893 | CDD:238020 | 20/107 (19%) | ||
| FN3 | 901..1005 | CDD:238020 | 15/108 (14%) | ||
| fn3 | 1011..1094 | CDD:278470 | 22/104 (21%) | ||
| FN3 | 1108..1202 | CDD:238020 | 25/114 (22%) | ||
| FN3 | 1210..1308 | CDD:238020 | 21/111 (19%) | ||
| fn3 | 1317..1402 | CDD:278470 | 24/92 (26%) | ||
| FN3 | 1415..1507 | CDD:238020 | 21/145 (14%) | ||
| FN3 | 1513..1608 | CDD:238020 | 21/110 (19%) | ||
| fn3 | 1617..1708 | CDD:278470 | 1/2 (50%) | ||
| FN3 | 1722..1823 | CDD:238020 | |||
| FN3 | 1828..1920 | CDD:238020 | |||
| FN3 | 1927..2016 | CDD:238020 | |||
| IL6ST | NP_002175.2 | Lep_receptor_Ig | 26..112 | CDD:283889 | 19/99 (19%) |
| FN3 | 121..215 | CDD:304408 | 19/122 (16%) | ||
| FN3 | 222..321 | CDD:238020 | 22/102 (22%) | ||
| WSXWS motif | 310..314 | 0/3 (0%) | |||
| FN3 | 519..599 | CDD:214495 | 26/93 (28%) | ||
| Box 1 motif | 651..659 | 3/7 (43%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 660..681 | 3/20 (15%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 722..758 | 4/35 (11%) | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.910 | |||||