DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sdk and DIP-theta

DIOPT Version :9

Sequence 1:	NP_001284756.1	Gene:	sdk / 31017	FlyBaseID:	FBgn0021764	Length:	2265	Species:	Drosophila melanogaster
Sequence 2:	NP_723103.1	Gene:	DIP-theta / 33795	FlyBaseID:	FBgn0051646	Length:	606	Species:	Drosophila melanogaster

Alignment Length:	294	Identity:	71/294 - (24%)
Similarity:	117/294 - (39%)	Gaps:	56/294 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   489 DRRKEFRFASAPIMELPP-----QNVTALDGKDATISCRAVGSPNPNITWIYNETQ--------L 540
            |.|::....:.|..:||.     ||||....::|.:.|.........|.|:..:||        :
  Fly   114 DIREDTVVNAIPEKDLPKFGELLQNVTVPVSREAVLQCVVDNLQTYKIAWLRVDTQTILTIQNHV 178

  Fly   541 VDISSRVQILESGD----LLISNIRSVDAGLYIC-VRANEAGSVKGEAYLSVLVRTQIIQPPVDT 600
            :..:.|:.|..:..    |.|.:::..|.|.|:| :..:...|..|  ||.|:|...|:..|..|
  Fly   179 ITKNHRMSITHAEKRAWILRIRDVKESDKGWYMCQINTDPMKSQVG--YLDVVVPPDILDYPTST 241

  Fly   601 TVLL--GLTATLQCKVSSDPSVPYNIDWYREGQSSTPISNSQRIGVQADGQLEIQAVRASDVGSY 663
            .:::  |...||:|..:..|:.  .|.|.|||....|:.|...........|.|..|...::|:|
  Fly   242 DMVIREGSNVTLKCAATGSPTP--TITWRREGGELIPLPNGAEAVAYNGSFLTIAKVNRLNMGAY 304

  Fly   664 ACVVTSPGGNETRAARLSVIELPFPP--------------SNVKVERLPEPQQRSINVSW----- 709
            .| :.|.|...|.:.|:.:| :.|||              .|:.:|...|...:|||. |
  Fly   305 LC-IASNGIPPTVSKRVMLI-VHFPPMIWIQNQLVGAALTQNITLECQSEAYPKSINY-WMKNDT 366

  Fly   710 --TPG-------FDGNSPIS-KFIIQRREVSELG 733
              .||       |:....|: :..|...::.:.|
  Fly   367 IIVPGERFVPETFESGYKITMRLTIYEVDIQDFG 400

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sdk	NP_001284756.1	Ig	71..157	CDD:299845
		I-set	72..150	CDD:254352
		Ig	172..245	CDD:299845
		IG_like	280..356	CDD:214653
		Ig	280..343	CDD:299845
		IG_like	375..450	CDD:214653
		Ig	378..447	CDD:143165
		Ig	506..587	CDD:299845	22/98 (22%)
		IG_like	506..587	CDD:214653	22/98 (22%)
		I-set	592..682	CDD:254352	25/91 (27%)
		Ig	595..682	CDD:299845	24/88 (27%)
		FN3	686..789	CDD:238020	16/77 (21%)
		FN3	798..893	CDD:238020
		FN3	901..1005	CDD:238020
		fn3	1011..1094	CDD:278470
		FN3	1108..1202	CDD:238020
		FN3	1210..1308	CDD:238020
		fn3	1317..1402	CDD:278470
		FN3	1415..1507	CDD:238020
		FN3	1513..1608	CDD:238020
		fn3	1617..1708	CDD:278470
		FN3	1722..1823	CDD:238020
		FN3	1828..1920	CDD:238020
		FN3	1927..2016	CDD:238020
DIP-theta	NP_723103.1	Ig	137..230	CDD:299845	23/94 (24%)
		IG_like	137..230	CDD:214653	23/94 (24%)
		IG_like	240..324	CDD:214653	24/87 (28%)
		IGc2	247..310	CDD:197706	18/65 (28%)
		Ig	327..419	CDD:299845	15/75 (20%)
		IG_like	343..420	CDD:214653	13/59 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810