DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment sdk and dpr3

DIOPT Version :9

Sequence 1:NP_001284756.1 Gene:sdk / 31017 FlyBaseID:FBgn0021764 Length:2265 Species:Drosophila melanogaster
Sequence 2:NP_001014459.2 Gene:dpr3 / 3346208 FlyBaseID:FBgn0053516 Length:522 Species:Drosophila melanogaster


Alignment Length:291 Identity:66/291 - (22%)
Similarity:97/291 - (33%) Gaps:100/291 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly   475 AGLGSE-------KGSESGSSDRRKE--FRFASAPIMEL-PPQNVTALDG-KDATISCRAVGSPN 528
            |..||:       |...||::|...:  ....|.||.:. .|:|:|...| .:|.|.||.....:
  Fly   202 ASFGSDLFAQTDAKRERSGAADEESQDADTSQSLPIFDFGMPRNITGRTGHTEAIIKCRVDSLHD 266

  Fly   529 PNITWIYNE--------TQLVDISSRVQILESGD-----LLISNIRSVDAGLYICVRANEAGSVK 580
            .:::||...        |.......|.|:.||.|     |.:....:.|:|:|.|       .|.
  Fly   267 KSVSWIRKRDLHILTVGTATYTSDKRFQVTESKDSREWTLHVKAPLAKDSGIYEC-------QVN 324

  Fly   581 GEAYLSVLVRTQIIQ-----------PPVDTTVLLGLTATLQCKVSSDPSV----PYNIDWYR-- 628
            .|..:|:..:..||:           || |.....|....|.|.| ..|||    |  |.|||  
  Fly   325 TEPKMSMAFQLNIIEISPDAKAVISGPP-DLHFKAGSAIILNCLV-QQPSVKDIGP--IYWYRGE 385

  Fly   629 ---------EGQSSTP--------------------------------ISNSQRIGVQADGQLEI 652
                     :||...|                                |:...::|.....:|.|
  Fly   386 HMITPFDADDGQPEIPAGRGEHPQGIPEDTSPNDIMSEVDLQMEFATRIAMESQLGDTLKSRLRI 450

  Fly   653 QAVRASDVGSYACVVTSPGGNETRAARLSVI 683
            ...:.:|.|:|.|       ..|.|:..||:
  Fly   451 SNAQTTDTGNYTC-------QPTTASSASVL 474

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
sdkNP_001284756.1 Ig 71..157 CDD:299845
I-set 72..150 CDD:254352
Ig 172..245 CDD:299845
IG_like 280..356 CDD:214653
Ig 280..343 CDD:299845
IG_like 375..450 CDD:214653
Ig 378..447 CDD:143165
Ig 506..587 CDD:299845 23/94 (24%)
IG_like 506..587 CDD:214653 23/94 (24%)
I-set 592..682 CDD:254352 30/147 (20%)
Ig 595..682 CDD:299845 28/144 (19%)
FN3 686..789 CDD:238020
FN3 798..893 CDD:238020
FN3 901..1005 CDD:238020
fn3 1011..1094 CDD:278470
FN3 1108..1202 CDD:238020
FN3 1210..1308 CDD:238020
fn3 1317..1402 CDD:278470
FN3 1415..1507 CDD:238020
FN3 1513..1608 CDD:238020
fn3 1617..1708 CDD:278470
FN3 1722..1823 CDD:238020
FN3 1828..1920 CDD:238020
FN3 1927..2016 CDD:238020
dpr3NP_001014459.2 Ig 243..330 CDD:299845 23/93 (25%)
IG_like 243..329 CDD:214653 23/92 (25%)
Ig 350..464 CDD:299845 26/124 (21%)
IG_like <441..477 CDD:214653 11/41 (27%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.810

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