DRSC/TRiP Functional Genomics Resources

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Protein Alignment sdk and Opcml

DIOPT Version :9

Sequence 1:NP_001284756.1 Gene:sdk / 31017 FlyBaseID:FBgn0021764 Length:2265 Species:Drosophila melanogaster
Sequence 2:XP_006510497.1 Gene:Opcml / 330908 MGIID:97397 Length:354 Species:Mus musculus


Alignment Length:374 Identity:78/374 - (20%)
Similarity:123/374 - (32%) Gaps:111/374 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly   252 SGDPYIEVAPEIIVRPQDVKVKVGTGVVELQCIANARPLHELETLWLKDGLAVETAGVRHTL--- 313
            |||.....|.:      :|.|:.|.... |:|..:.|   .....||.          |.|:   
Mouse    33 SGDATFPKAMD------NVTVRQGESAT-LRCTIDDR---VTRVAWLN----------RSTILYA 77

  Fly   314 -NDPWN---RTLALLQANSSHS-----------GEYTCQVRLRSGGYPAVSASARLQILEPPLFF 363
             ||.|:   |.:.|:...:.:|           |.|||.|  ::..:|..| ...|.:..||...
Mouse    78 GNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSV--QTDNHPKTS-RVHLIVQVPPQIM 139

  Fly   364 TPMRAETFGEFGGQVQLTCDVVGEPTPQVKWFRNAESVDAH--IESGRYTLNTDNTLVIKKLILD 426
            ......|..| |..|.|.|..:|.|.|.|.|        .|  ::.|:..::.|..|.|..:..|
Mouse   140 NISSDITVNE-GSSVTLLCLAIGRPEPTVTW--------RHLSVKEGQGFVSEDEYLEISDIKRD 195

  Fly   427 DAAMFQCLAINEAGENSASTWLRVKTKTAKNRVKRLAQPRILRVRASHAGLGSEKGSESGSSDRR 491
            .:..::|.|:|:                       :|.|.:.:|:.:                  
Mouse   196 QSGEYECSALND-----------------------VAAPDVRKVKIT------------------ 219

  Fly   492 KEFRFASAPIMELPP-----QNVTALDGKDATISCRAVGSPNPNITWIYNETQLVDISSRVQILE 551
                      :..||     :|.....|:...:||.|...|.....|...:|:|......|:|..
Mouse   220 ----------VNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEDTRLATGLDGVRIEN 274

  Fly   552 SG---DLLISNIRSVDAGLYICVRANEAGSVKGEAYLSVLVRTQIIQPP 597
            .|   .|...|:...|.|.|.||..|:.|:......|..:..:..:..|
Mouse   275 KGRISTLTFFNVSEKDYGNYTCVATNKLGNTNASITLYEISPSSAVAGP 323

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
sdkNP_001284756.1 Ig 71..157 CDD:299845
I-set 72..150 CDD:254352
Ig 172..245 CDD:299845
IG_like 280..356 CDD:214653 21/93 (23%)
Ig 280..343 CDD:299845 18/80 (23%)
IG_like 375..450 CDD:214653 18/76 (24%)
Ig 378..447 CDD:143165 17/70 (24%)
Ig 506..587 CDD:299845 23/88 (26%)
IG_like 506..587 CDD:214653 23/88 (26%)
I-set 592..682 CDD:254352 1/6 (17%)
Ig 595..682 CDD:299845 1/3 (33%)
FN3 686..789 CDD:238020
FN3 798..893 CDD:238020
FN3 901..1005 CDD:238020
fn3 1011..1094 CDD:278470
FN3 1108..1202 CDD:238020
FN3 1210..1308 CDD:238020
fn3 1317..1402 CDD:278470
FN3 1415..1507 CDD:238020
FN3 1513..1608 CDD:238020
fn3 1617..1708 CDD:278470
FN3 1722..1823 CDD:238020
FN3 1828..1920 CDD:238020
FN3 1927..2016 CDD:238020
OpcmlXP_006510497.1 Ig 44..132 CDD:416386 24/104 (23%)
Ig strand A' 44..49 CDD:409353 2/4 (50%)
Ig strand B 51..59 CDD:409353 2/8 (25%)
CDR1 59..63 CDD:409353 1/6 (17%)
FR2 64..70 CDD:409353 1/5 (20%)
Ig strand C 64..70 CDD:409353 1/5 (20%)
CDR2 71..83 CDD:409353 4/11 (36%)
Ig strand C' 72..76 CDD:409353 1/3 (33%)
Ig strand C' 80..83 CDD:409353 1/2 (50%)
FR3 84..118 CDD:409353 8/35 (23%)
Ig strand D 87..94 CDD:409353 2/6 (33%)
Ig strand E 97..103 CDD:409353 1/5 (20%)
Ig strand F 110..118 CDD:409353 5/9 (56%)
CDR3 119..123 CDD:409353 0/3 (0%)
Ig strand G 123..132 CDD:409353 3/9 (33%)
FR4 125..132 CDD:409353 2/7 (29%)
Ig_3 135..206 CDD:404760 21/79 (27%)
Ig strand A 135..138 CDD:409353 2/2 (100%)
Ig strand A' 144..148 CDD:409353 1/3 (33%)
Ig strand B 151..160 CDD:409353 3/8 (38%)
Ig strand C 165..170 CDD:409353 3/12 (25%)
Ig strand C' 171..174 CDD:409353 1/2 (50%)
Ig strand F 198..206 CDD:409353 2/7 (29%)
Ig_3 223..300 CDD:404760 21/76 (28%)
putative Ig strand A 224..230 CDD:409353 1/5 (20%)
Ig strand B 240..244 CDD:409353 0/3 (0%)
Ig strand C 253..257 CDD:409353 0/3 (0%)
Ig strand E 279..283 CDD:409353 1/3 (33%)
Ig strand F 293..298 CDD:409353 2/4 (50%)
Ig strand G 306..309 CDD:409353 0/2 (0%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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