DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment sdk and Kirrel1

DIOPT Version :9

Sequence 1:NP_001284756.1 Gene:sdk / 31017 FlyBaseID:FBgn0021764 Length:2265 Species:Drosophila melanogaster
Sequence 2:XP_006232737.1 Gene:Kirrel1 / 310695 RGDID:727883 Length:805 Species:Rattus norvegicus


Alignment Length:783 Identity:168/783 - (21%)
Similarity:257/783 - (32%) Gaps:246/783 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly   255 PYIEVAPEIIV---------------RPQDVKVKVGTGVVELQCI-ANARPLHELETLWLKDGLA 303
            |::.||..|.|               .|.|..|..|...| |.|: .|...:.:    |.|||||
  Rat    32 PHLVVAYLIFVTLALALPGTQTRFSQEPADQTVVAGHRAV-LPCVLLNYSGIVQ----WTKDGLA 91

  Fly   304 VETAGVRHTLNDPWNR------------TLALLQANSSHSGEYTCQ---VRLRSGGYPAVSASAR 353
            :   |:...|. .|.|            .|.:..|..|....|.||   ..||       |..|:
  Rat    92 L---GMGQGLK-AWPRYRVVGSADAGQYNLEITDAELSDDASYECQATEAALR-------SRRAK 145

  Fly   354 LQILEPPLFFTPMRAETFGEFGGQV---------QLTCDVV-GEPTPQVKWFRNAESVDAHIESG 408
            |.:|.||        |.....||.|         .|||... .:|...:.|||:....:..:.|.
  Rat   146 LTVLIPP--------EDTRIDGGPVILLQAGTPYNLTCRAFNAKPAATIIWFRDGTQQEGAVTST 202

  Fly   409 RYTLN-----TDNTLVIKKLILDDAAMFQCLAINEAGENSASTWLRV--------------KTKT 454
            ....:     |.:.|:|:...||...:|.|.::|||..|...|.:.:              :|..
  Rat   203 ELLKDGKRETTISQLLIQPTDLDIGRVFTCRSMNEAIPNGKETSIELDVHHPPTVTLSIEPQTVL 267

  Fly   455 AKNRV----KRLAQPRILRVRASHAGLGSEKGSES-----------------------GSSDRRK 492
            ...||    :..|.|.||..|.:..|...|...||                       ||::...
  Rat   268 EGERVIFTCQATANPEILGYRWAKGGFLIEDAHESRYETNVDYSFFTEPVSCEVYNKVGSTNVST 332

  Fly   493 EFRFASAPIMELPPQNVTALDGKDATISCRAVGSPNPNITWIYNETQL----------VDISSRV 547
            ......||.:.:.|:..|...|.|.|::|..||:|...:||...::.:          .::|::|
  Rat   333 LVNVHFAPRIVVYPKPTTTDIGSDVTLTCVWVGNPPLTLTWTKKDSNMGPRLPGSPPEANLSAQV 397

  Fly   548 QILESGDLLISNIRSVDAGLYICVRA--NEAGSVKGEAYLSV----LVRTQIIQPPVDTTVLLGL 606
             :..|..||:.::...|||.|.| ||  ...|..:.|..|.|    ::.::.:|     ..:.|.
  Rat   398 -LSNSNQLLLKSVTQADAGTYTC-RAIVPRIGVAEREVPLYVNGPPIISSEAVQ-----FAVRGD 455

  Fly   607 TATLQCKVSSDPSVPYNIDW-YREGQSSTPISNSQRIGVQADGQ-------LEIQAVRASDVGS- 662
            ...::|.:.|.|. |..|.| ::|  :...:...:|..|:....       |.|..|..:|..: 
  Rat   456 GGKVECFIGSTPP-PDRIAWAWKE--NFLEVGTLERYTVERTNSGSGVLSTLTINNVMEADFQTH 517

  Fly   663 YACVVTSPGGNETRAARLSVIE-LP--------------------------------------FP 688
            |.|...:..|..|...:|...| ||                                      ..
  Rat   518 YNCTAWNSFGPGTAIIQLEEREVLPVGIIAGATIGAGILLVFSFAALVFFLYRRRKGSRKDVTLR 582

  Fly   689 PSNVKVERL-PEP-------------------QQRSINVSWTPGFDGNSPISKFIIQRREVSELG 733
            ..::|||.: .||                   ..::|..|:....|....:....|:.||..|: 
  Rat   583 KLDIKVETVNREPLTMHSDREDDTTSISTATRVMKAIYSSFKDDVDLKQDLHCDTIETREEYEM- 646

  Fly   734 PVPDPLLNWITELSNVSADQ-----RWILLENLKAATVYQFRVSAVNRVGEGSP----SEPSNVV 789
              .||...:.    ||.|.:     |.:|..:.:|....:|         :|.|    |..|...
  Rat   647 --KDPTNGYY----NVRAHEDRPSSRAVLYADYRAPGPTRF---------DGRPSSRLSHSSGYA 696

  Fly   790 EL------------PQEAPSGPPVGFVGSARSMSEIITQWQPPLEEHRNGQILGYILRYRLFGYN 842
            :|            .:..||||..  .|...:.|::..:.......|......|| ..||| ||.
  Rat   697 QLNTYSRAPASDYGTEPTPSGPSA--PGGTDTTSQLSYENYEKFNSHPFPGAAGY-PTYRL-GYP 757

  Fly   843 NVP 845
            ..|
  Rat   758 QAP 760

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
sdkNP_001284756.1 Ig 71..157 CDD:299845
I-set 72..150 CDD:254352
Ig 172..245 CDD:299845
IG_like 280..356 CDD:214653 24/91 (26%)
Ig 280..343 CDD:299845 21/78 (27%)
IG_like 375..450 CDD:214653 23/89 (26%)
Ig 378..447 CDD:143165 20/83 (24%)
Ig 506..587 CDD:299845 26/92 (28%)
IG_like 506..587 CDD:214653 26/92 (28%)
I-set 592..682 CDD:254352 20/98 (20%)
Ig 595..682 CDD:299845 20/95 (21%)
FN3 686..789 CDD:238020 26/169 (15%)
FN3 798..893 CDD:238020 13/48 (27%)
FN3 901..1005 CDD:238020
fn3 1011..1094 CDD:278470
FN3 1108..1202 CDD:238020
FN3 1210..1308 CDD:238020
fn3 1317..1402 CDD:278470
FN3 1415..1507 CDD:238020
FN3 1513..1608 CDD:238020
fn3 1617..1708 CDD:278470
FN3 1722..1823 CDD:238020
FN3 1828..1920 CDD:238020
FN3 1927..2016 CDD:238020
Kirrel1XP_006232737.1 I-set 54..148 CDD:254352 29/109 (27%)
Ig 57..148 CDD:299845 29/106 (27%)
Ig2_KIRREL3-like 170..251 CDD:143236 20/80 (25%)
I-set 255..336 CDD:254352 14/80 (18%)
Ig_2 259..337 CDD:290606 14/77 (18%)
Ig_2 340..437 CDD:290606 27/98 (28%)
IG_like 346..437 CDD:214653 26/92 (28%)
Ig5_KIRREL3 439..536 CDD:143306 19/104 (18%)
IG_like 451..536 CDD:214653 18/87 (21%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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