DRSC/TRiP Functional Genomics Resources

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Protein Alignment sdk and Iglon5

DIOPT Version :9

Sequence 1:NP_001284756.1 Gene:sdk / 31017 FlyBaseID:FBgn0021764 Length:2265 Species:Drosophila melanogaster
Sequence 2:NP_001157990.1 Gene:Iglon5 / 210094 MGIID:2686277 Length:336 Species:Mus musculus


Alignment Length:386 Identity:95/386 - (24%)
Similarity:139/386 - (36%) Gaps:94/386 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly   344 GYPAVSASARLQILEPPLFFTPMRAETFGEFGGQVQLTCDVVGEPTPQVKWFRNAESVDAHIESG 408
            |...:|.....|.||   |.:|....|..| |....|:| .:.|...:|.|              
Mouse    20 GLAVISRGLLSQSLE---FSSPADNYTVCE-GDNATLSC-FIDEHVTRVAW-------------- 65

  Fly   409 RYTLNTDNTLVIKKLILDDAAMFQCLAINEAGENSASTWLRVKTKTAKNRVKRLAQ-PRILRVRA 472
               ||..|.|.                   ||.:   .|      |:..||:.|.. |....:..
Mouse    66 ---LNRSNILY-------------------AGND---RW------TSDPRVRLLINTPEEFSILI 99

  Fly   473 SHAGLGSEKGSESGSSDRRKEFRFASAPIMELPPQ------NVTALDGKDATISCRAVGSPNPNI 531
            :..|||.|.........|.:.:......|:.:|.:      .|...:|.:..:.|.|||.|.|.:
Mouse   100 TQVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVAVNEGGNVNLLCLAVGRPEPTV 164

  Fly   532 TWIYNETQLVD-ISSRVQILESGDLLISNIRSVDAGLYICVRANEAGSVKGEAYLSVLVRTQIIQ 595
            ||    .||.| .:|..:|||     ||:|:...||.|.||..|...|......:.|.|.    .
Mouse   165 TW----RQLRDGFTSEGEILE-----ISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTVN----Y 216

  Fly   596 PPVDTTV-----LLGLTATLQCKVSSDPSVPYNIDWYREGQ--SSTPISNSQRIGVQAD---GQL 650
            ||..|.|     .||..|.|:|:..:.|  |.:..||::.:  ||   .:::.:.||.:   ..|
Mouse   217 PPTITDVTSARTALGRAALLRCEAMAVP--PADFQWYKDDRLLSS---GSAEGLKVQTERTRSML 276

  Fly   651 EIQAVRASDVGSYACVVTSPGGNETRAARLSVIELPFPPSNVK--VERLPEPQQRSINVSW 709
            ....|.|...|:|.|...:..|..:.:.||      ..|.:::  ..|.|.|......:||
Mouse   277 LFANVSARHYGNYTCRAANRLGASSASMRL------LRPGSLENSAPRPPGPLTLLSALSW 331

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
sdkNP_001284756.1 Ig 71..157 CDD:299845
I-set 72..150 CDD:254352
Ig 172..245 CDD:299845
IG_like 280..356 CDD:214653 2/11 (18%)
Ig 280..343 CDD:299845
IG_like 375..450 CDD:214653 13/74 (18%)
Ig 378..447 CDD:143165 11/68 (16%)
Ig 506..587 CDD:299845 27/87 (31%)
IG_like 506..587 CDD:214653 27/87 (31%)
I-set 592..682 CDD:254352 26/99 (26%)
Ig 595..682 CDD:299845 26/96 (27%)
FN3 686..789 CDD:238020 6/26 (23%)
FN3 798..893 CDD:238020
FN3 901..1005 CDD:238020
fn3 1011..1094 CDD:278470
FN3 1108..1202 CDD:238020
FN3 1210..1308 CDD:238020
fn3 1317..1402 CDD:278470
FN3 1415..1507 CDD:238020
FN3 1513..1608 CDD:238020
fn3 1617..1708 CDD:278470
FN3 1722..1823 CDD:238020
FN3 1828..1920 CDD:238020
FN3 1927..2016 CDD:238020
Iglon5NP_001157990.1 Ig 41..129 CDD:416386 25/134 (19%)
Ig strand A' 41..46 CDD:409353 1/4 (25%)
Ig strand B 48..56 CDD:409353 2/8 (25%)
CDR1 56..60 CDD:409353 1/3 (33%)
FR2 61..68 CDD:409353 3/23 (13%)
Ig strand C 61..67 CDD:409353 2/22 (9%)
CDR2 69..79 CDD:409353 4/31 (13%)
Ig strand C' 71..74 CDD:409353 1/21 (5%)
Ig strand C' 76..79 CDD:409353 0/5 (0%)
FR3 80..115 CDD:409353 9/34 (26%)
Ig strand D 84..91 CDD:409353 3/6 (50%)
Ig strand E 94..100 CDD:409353 0/5 (0%)
Ig strand F 107..115 CDD:409353 1/7 (14%)
CDR3 116..120 CDD:409353 1/3 (33%)
Ig strand G 120..129 CDD:409353 0/8 (0%)
FR4 122..129 CDD:409353 0/6 (0%)
Ig strand A 132..137 CDD:409353 1/4 (25%)
Ig_3 134..199 CDD:404760 25/73 (34%)
Ig strand A' 140..145 CDD:409353 1/4 (25%)
Ig strand B 148..157 CDD:409353 1/8 (13%)
Ig strand C 163..167 CDD:409353 2/7 (29%)
Ig strand D 174..177 CDD:409353 1/2 (50%)
Ig strand E 178..183 CDD:409353 3/9 (33%)
Ig strand F 191..199 CDD:409353 4/7 (57%)
Ig_3 217..295 CDD:404760 23/82 (28%)
putative Ig strand A 218..224 CDD:409353 2/5 (40%)
Ig strand B 234..238 CDD:409353 2/3 (67%)
Ig strand C 247..251 CDD:409353 0/3 (0%)
Ig strand E 274..278 CDD:409353 1/3 (33%)
Ig strand F 288..293 CDD:409353 2/4 (50%)
Ig strand G 301..304 CDD:409353 0/2 (0%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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