DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SkpA and skp1

DIOPT Version :9

Sequence 1:	NP_001033818.1	Gene:	SkpA / 31016	FlyBaseID:	FBgn0025637	Length:	162	Species:	Drosophila melanogaster
Sequence 2:	NP_957037.1	Gene:	skp1 / 393716	ZFINID:	ZDB-GENE-040426-1707	Length:	163	Species:	Danio rerio

Alignment Length:	163	Identity:	123/163 - (75%)
Similarity:	142/163 - (87%)	Gaps:	1/163 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPSIKLQSSDEEIFDTDIQIAKCSGTIKTMLEDCGMEDD-ENAIVPLPNVNSTILRKVLTWAHYH 64
            ||:|||||||.|:|:.|::|||.|.||||||||.||:|: ::..|||||||:.||:||:.|..:|
Zfish     1 MPTIKLQSSDGEMFEVDVEIAKQSVTIKTMLEDLGMDDEGDDDPVPLPNVNAAILKKVIQWCTHH 65

  Fly    65 KDDPQPTEDDESKEKRTDDIISWDADFLKVDQGTLFELILAANYLDIKGLLELTCKTVANMIKGK 129
            ||||.|.||||:||||||||..||.:|||||||||||||||||||||||||::||||||||||||
Zfish    66 KDDPPPPEDDENKEKRTDDIPVWDQEFLKVDQGTLFELILAANYLDIKGLLDVTCKTVANMIKGK 130

  Fly   130 TPEEIRKTFNIKKDFSPAEEEQVRKENEWCEEK 162
            ||||||||||||.||:..||.||||||:|||||
Zfish   131 TPEEIRKTFNIKNDFTEEEEAQVRKENQWCEEK 163

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SkpA	NP_001033818.1	BTB_POZ_SKP1	4..126	CDD:349631	89/122 (73%)
SkpA	NP_001033818.1	Skp1	112..159	CDD:396171	38/46 (83%)
skp1	NP_957037.1	BTB_POZ_SKP1	3..127	CDD:349631	89/123 (72%)
skp1	NP_957037.1	Skp1	113..160	CDD:396171	38/46 (83%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583352
Domainoid	1	1.000	89	1.000	Domainoid score	I7883
eggNOG	1	0.900	-	-		E1_COG5201
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H38775
Inparanoid	1	1.050	253	1.000	Inparanoid score	I3187
OMA	1	1.010	-	-		QHG54148
OrthoDB	1	1.010	-	-		D1412723at2759
OrthoFinder	1	1.000	-	-		FOG0000367
OrthoInspector	1	1.000	-	-		otm25944
orthoMCL	1	0.900	-	-		OOG6_100934
Panther	1	1.100	-	-	LDO	PTHR11165
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1343
SonicParanoid	1	1.000	-	-		X346
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800