DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SkpA and skr-20

DIOPT Version :9

Sequence 1:	NP_001033818.1	Gene:	SkpA / 31016	FlyBaseID:	FBgn0025637	Length:	162	Species:	Drosophila melanogaster
Sequence 2:	NP_510192.1	Gene:	skr-20 / 181445	WormBaseID:	WBGene00004826	Length:	173	Species:	Caenorhabditis elegans

Alignment Length:	150	Identity:	49/150 - (32%)
Similarity:	78/150 - (52%)	Gaps:	5/150 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 PSIKLQSSDEEIFDTDIQIAKCSGTIKTMLEDCGMEDD--ENAIVPLPNVNSTILRKVLTWAHYH 64
            |..||:|.|.:||:.:....|....|.....|.|:.|.  |.|...|...:|:|::.|:.|.:::
Worm     8 PLYKLKSEDGQIFNVERGPMKFCAFINQKFIDHGVNDRNCERADPILVPFHSSIVQAVIEWLYHY 72

  Fly    65 KDDPQPTEDDESKEKRTDDIISWDADFLKVDQGTLFELILAANYLDIKGLLELTCKTVANMIKGK 129
            :|:|....|.:.   |..|...||..|..|:.|.||.|:.|::.|.::.|:.:.|...|.:|:||
Worm    73 QDNPLARRDSKI---RYHDFSEWDKQFFNVESGVLFALLNASHALGVEDLMNMGCAAAAELIRGK 134

  Fly   130 TPEEIRKTFNIKKDFSPAEE 149
            :.|||||.:.|:.|....||
Worm   135 STEEIRKIYGIRSDEEQMEE 154

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SkpA	NP_001033818.1	BTB_POZ_SKP1	4..126	CDD:349631	36/123 (29%)
SkpA	NP_001033818.1	Skp1	112..159	CDD:396171	14/37 (38%)
skr-20	NP_510192.1	Skp1	7..116	CDD:214704	34/110 (31%)
skr-20	NP_510192.1	Skp1	90..154	CDD:279768	23/63 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160160693
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5201
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1412723at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11165
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.850