DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SkpA and skr-2

DIOPT Version :9

Sequence 1:	NP_001033818.1	Gene:	SkpA / 31016	FlyBaseID:	FBgn0025637	Length:	162	Species:	Drosophila melanogaster
Sequence 2:	NP_492512.1	Gene:	skr-2 / 172773	WormBaseID:	WBGene00004808	Length:	174	Species:	Caenorhabditis elegans

Alignment Length:	162	Identity:	92/162 - (56%)
Similarity:	120/162 - (74%)	Gaps:	7/162 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 IKLQSSDEEIFDTDIQIAKCSGTIKTMLEDCGMEDDE--NA-IVPLPNVNSTILRKVLTWAHYHK 65
            ||:.|||:|||.....:.:.|.|:.|:|.|.|::|||  || .:|:.||.::||:||:.|...|:
Worm    16 IKISSSDDEIFLVPRNVIRLSNTLNTLLVDLGLDDDEGTNAEPIPVQNVTASILKKVINWCTKHQ 80

  Fly    66 DDPQPTEDDESKEKRTD-DIISWDADFLKVDQGTLFELILAANYLDIKGLLELTCKTVANMIKGK 129
            .||.||||   .||:|| .|..||..||.:|||||||||||||||||||||::.|::||||||||
Worm    81 SDPIPTED---SEKKTDGSIQDWDKKFLDIDQGTLFELILAANYLDIKGLLDVACQSVANMIKGK 142

  Fly   130 TPEEIRKTFNIKKDFSPAEEEQVRKENEWCEE 161
            :|:|||:.||||.||:..|.||:||||.||::
Worm   143 SPDEIRRAFNIKDDFTAEEREQIRKENAWCDD 174

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SkpA	NP_001033818.1	BTB_POZ_SKP1	4..126	CDD:349631	68/125 (54%)
SkpA	NP_001033818.1	Skp1	112..159	CDD:396171	30/46 (65%)
skr-2	NP_492512.1	SKP1	16..174	CDD:227528	92/160 (58%)
		Skp1	16..124	CDD:214704	58/110 (53%)
		Skp1	99..172	CDD:279768	51/72 (71%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160160707
Domainoid	1	1.000	56	1.000	Domainoid score	I7318
eggNOG	1	0.900	-	-		E1_COG5201
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H38775
Inparanoid	1	1.050	217	1.000	Inparanoid score	I2312
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54148
OrthoDB	1	1.010	-	-		D1412723at2759
OrthoFinder	1	1.000	-	-		FOG0000367
OrthoInspector	1	1.000	-	-		mtm4845
orthoMCL	1	0.900	-	-		OOG6_100934
Panther	1	1.100	-	-	O	PTHR11165
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X346
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770