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Protein Alignment Hmt4-20 and kmt5b

DIOPT Version :9

Sequence 1:	NP_001245453.1	Gene:	Hmt4-20 / 31015	FlyBaseID:	FBgn0025639	Length:	1300	Species:	Drosophila melanogaster
Sequence 2:	NP_001007338.1	Gene:	kmt5b / 572849	ZFINID:	ZDB-GENE-041114-22	Length:	808	Species:	Danio rerio

Alignment Length:	1037	Identity:	308/1037 - (29%)
Similarity:	437/1037 - (42%)	Gaps:	283/1037 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    81 NQQHH--QVAHSQPHATHYQQTNQHPSHHHQSHQSSNGSGGGSAGSGSGSGSVVSGLNGCNGS-- 141
            |.:.|  :.:.:||.:....|..|      :||...|          .||.||......|.|:
Zfish    10 NGRRHGRKFSSNQPVSKSRLQNTQ------RSHLRQN----------KGSPSVRRCSRRCGGAPP 58

  Fly   142 -AVSRLSQSTGMSPRELSENDDLATSLILDPHLGFQTHKMNIRFRPLKVDTQQLKAIVDDFIHTQ 205
             |..|...|:||:.:||.|.|||:|||||||:|||||||||.||||:|...::|:.|::.|....
Zfish    59 EAERRHVPSSGMTAKELCEYDDLSTSLILDPYLGFQTHKMNTRFRPIKGRQRELREIIELFKKHD 123

  Fly   206 NYDIAIQRIYEGPWIPRHLKNKNKIATKRLHDHIVRYLRVFDKDSGFAIEACYRYTLEEQRGAKI 270
            |.:.|.|.:..|.|...|..||.|...|....|:..|||:|..||||.|.:|.||: .||.||||
Zfish   124 NLEKAFQALTSGDWTRHHFLNKTKSQEKLFKAHVFVYLRMFASDSGFEILSCNRYS-SEQNGAKI 187

  Fly   271 SSTKRWSKNDKIECLVGCIAELTEAEEAALLHSGKNDFSVMYSCRKNCAQLWLGPAAYINHDCRA 335
            .:||.|.:|||||.||||||||:.:||..||..|:||||||||.|||||||||||||:||||||.
Zfish   188 VATKDWKRNDKIEHLVGCIAELSPSEERMLLRHGENDFSVMYSTRKNCAQLWLGPAAFINHDCRP 252

  Fly   336 NCKFLATGRDTACVKVLRDIEVGEEITCFYGEDFFGDSNRYCECETCERRGTGAFAGKDDGLMLG 400
            ||||::|||||||||||||||.||||:|:||:.|||::|.:|||.||||||||||..|.
Zfish   253 NCKFVSTGRDTACVKVLRDIEPGEEISCYYGDGFFGENNEFCECYTCERRGTGAFKSKP------ 311

  Fly   401 LSMGLGLASSGPGNNGGYRLRETDNRINRIK----------SRANSTNSTSNSNSNTNDSTGPSE 455
                 ||....|..|..|.|||||.|:||:|          |::.|:|:.::|...|...|...:
Zfish   312 -----GLPVEAPVINSKYGLRETDKRLNRLKKLGESCRNSDSQSVSSNAEADSQEPTTVQTSLRK 371

  Fly   456 TSSTNGLVASGGAGGATGAAMLPTPSQQSTGGKEATAAVSLLEKKLPNVVVSPLTMKELRQKGMT 520
            .:|.:.:...|.|...|...:..|||..|: .|.:.|.:|.|.|:|.:.....|:....|.:|:.
Zfish   372 RTSQSCVKKHGEAKAVTRQTLSSTPSSTSS-SKRSQANISSLPKRLKSKPTQTLSKGRRRCRGLW 435

  Fly   521 KYDAEMIMANAAYQQQHHHQHHFHHHHHHHHHHHNHGQHASTGAEATAAVQQMAAMQKPGVGGTG 585
            ...:..:.|:...::.....             .:..:.||.|:.|.::....::
Zfish   436 TKGSSRVSASGNLKESSRRD-------------TDRRRSASKGSVARSSENNRSS---------- 477

  Fly   586 AAGNAGATTVSSVAAGAGSEVNGGRSTSLRKSMRVNSTSSSISTASADEVIAPVVAASISLPSKA 650
               :.||:..              :.::|.......||.:|:....|:...|....||.|:..|:
Zfish   478 ---SKGASPC--------------KDSTLCPYRTRRSTRTSLGAQGAEGTEASNHPASPSIVLKS 525

  Fly   651 -PVVLMPRCKPAQMAIAALHQSQQRQ---LRRSERQKEKLTDGESSDTSSEQQKKEQKQQDHQLP 711
             |...:|.....||:..:|..|..::   .||....|::.:.||
Zfish   526 EPGEFIPVTPGHQMSTPSLDSSCPKKGTCPRRRRTVKQEDSYGE--------------------- 569

  Fly   712 QKMFSLAEEPQPEKSEEKQQEQQKRVTRNSAGRVGLVARLATAHNNNIATTTNSSSSSNKATTIT 776
                |..:|..|:     .:...:.......|:|  |..|...|.:     .|.||.|:||  :.
Zfish   570 ----SFVQEGVPD-----LRHAVRAADVADCGKV--VLGLPDRHQH-----YNGSSKSSKA--LR 616

  Fly   777 NCNNHNSNNSSR------INHNSNLSSRLSVKSRKPAPSEASSIPSSTSSENQQQQATRRSCSPT 835
            ..........:|      :.:||.: .:::::.|:          .|:||:|:.::.:..|.|..
Zfish   617 RGKGKKKRQITRYDAQLILQNNSGI-PKITLRRRR----------DSSSSKNEPRETSSSSSSKI 670

  Fly   836 PAYKKNLLASFDPDPPSTQGIKEQLKDESVTYSPVKQKRSRRAAALAAAQSIHCEALGGFPTGST 900
                            |.:..||..||.|.:|          .|.|.          .||..|..
Zfish   671 ----------------SIKFSKEHEKDRSSSY----------VAKLN----------NGFSHGPH 699

  Fly   901 GSQRKRAQAGEPTTSCSSTTISNVEPLLKTPERRLKLTLRMKRSPILDEVIELGTSLSNGGAGRG 965
            .|..|                             ||:.|:.:..|         .||
Zfish   700 SSSTK-----------------------------LKIQLKREEDP---------ASL-------- 718

  Fly   966 APGSHR----EGTAG--EGSVRSALNLTGSSSNGIEYEILRMEGISEHGNDDDEDEEEDDEEPAA 1024
                ||    :.|.|  :......|:...::..|.:.|:   |.:|...:|||..:.|||..|
Zfish   719 ----HRTYPEDVTLGIVQRDAADVLDHKAAAQVGQDMEV---ESMSSEDDDDDYFDNEDDFIP-- 774

  Fly  1025 EEEEEPPPKEELQLVNKKQRKKQRSRSRSSQRRSPAPSSVYGTPQKKRLRLIFGNESHTIDI 1086
                                                      .|..||||||.|.:|..|||
Zfish   775 ------------------------------------------LPPAKRLRLIVGKDSIDIDI 794

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.