DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Hmt4-20 and set9

DIOPT Version :9

Sequence 1:	NP_001245453.1	Gene:	Hmt4-20 / 31015	FlyBaseID:	FBgn0025639	Length:	1300	Species:	Drosophila melanogaster
Sequence 2:	NP_588078.1	Gene:	set9 / 2539545	PomBaseID:	SPCC4B3.12	Length:	441	Species:	Schizosaccharomyces pombe

Alignment Length:	301	Identity:	86/301 - (28%)
Similarity:	142/301 - (47%)	Gaps:	59/301 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   161 DDLATSLILDPHLGF-QTHKMNIRFRPL------KVDTQQLKAIVDDFIHTQ-NYDIAIQRIYE- 216
            ||:.|.|::|....: |.||:    |.|      ::::..:..|:..:|..| :.|.|.:.|.:
pombe    15 DDVCTCLLVDKVFYWSQIHKV----RKLVDRSIERMESCSIINIITKYIIEQTDLDQAAKNILQF 75

  Fly   217 ---GPWIPRHLKNKNKIATKRLHDHIVRYLRVFDKDSGFAIEACYRYTLEEQRGAKISSTKRWSK 278
               .|.: |.|.:.:.:|..|   |:..||.::.....|.|.:..:|....:..|.:.:.:..:.
pombe    76 RELDPLL-RRLSSTSLLAFTR---HLKYYLSLYLPSCKFEICSTNQYFSSSKPEACVIARESINA 136

  Fly   279 NDKIECLVGCIAELTEAEEAALLHSGKNDFSVMYSCRKNCAQLWLGPAAYINHDCRANCKFLATG 343
            .:.|..|.|.|.:|:..||.. :..|| |||:::|.|.:...|:||||.::||||.|||:|..:|
pombe   137 GEDITDLCGTIIKLSPKEERN-IGIGK-DFSILHSSRLDSMCLFLGPARFVNHDCNANCRFNTSG 199

  Fly   344 RDTACVKVLRDIEVGEEITCFYGEDFFGDSNRYCECETCERRGTGAFAGKDDGLMLGLSMGLGLA 408
            : ...::.:|||:.|||||.||..::||..|..|.|.:|||.|.
pombe   200 K-RIWLRCVRDIKPGEEITTFYSSNYFGLENCECLCVSCERMGI--------------------- 242

  Fly   409 SSGPGNNGGYRLRETDNRINRIKSRANSTNSTSNSNSNTND 449
                  ||..:|..|.         |.||:.:|.|:|:.:|
pombe   243 ------NGFKKLFHTS---------ATSTSCSSKSSSDVSD 268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hmt4-20	NP_001245453.1	SET	256..372	CDD:214614	41/115 (36%)
set9	NP_588078.1	SET	1..430	CDD:225491	86/301 (29%)
set9	NP_588078.1	SET	127..220	CDD:279228	36/95 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	55	1.000	Domainoid score	I3198
eggNOG	1	0.900	-	-		E1_COG1437
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002279
OrthoInspector	1	1.000	-	-		oto100813
orthoMCL	1	0.900	-	-		OOG6_104297
Panther	1	1.100	-	-	LDO	PTHR12977
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1322
SonicParanoid	1	1.000	-	-		X2124
TreeFam	0	0.000	Not matched by this tool.
	8	7.930