Protein Alignment Roc1a and RBX1

DIOPT Version :9

• Sequence 1: NP_001138143.2
• Gene: Roc1a / 31014
• FlyBaseID: FBgn0025638
• Length: 136
• Species: Drosophila melanogaster
• Sequence 2: NP_055063.1
• Gene: RBX1 / 9978
• HGNCID: 9928
• Length: 108
• Species: Homo sapiens
• Alignment Length: 137
• Identity: 95/137 - (69%)
• Similarity: 99/137 - (72%)
• Gaps: 34/137 - (24%)

  Fly     1 MEVDEDGYEVPSSSSKG-DKKRFEVKKVSGQQKSRVIVNECTDGNTSSFPLRRKQWNAVALWAWD 64
            |:||     .||.::.| .||||||||                            ||||||||||
Human     5 MDVD-----TPSGTNSGAGKKRFEVKK----------------------------WNAVALWAWD 36

  Fly    65 IVVDNCAICRNHIMDLCIECQANQASATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREW 129
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Human    37 IVVDNCAICRNHIMDLCIECQANQASATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREW 101

  Fly   130 DFQKYGH 136
            :||||||
Human   102 EFQKYGH 108

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Roc1a	NP_001138143.2	APC11	53..136	CDD:227521	79/82 (96%)
		zf-rbx1	53..126	CDD:289448	70/72 (97%)
RBX1	NP_055063.1	mRING-H2-C3H2C2D_RBX1	40..101	CDD:319399	60/60 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165159922
Domainoid	1	1.000	138	1.000	Domainoid score	I4880
eggNOG	1	0.900	-	-		E1_COG5194
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6872
Inparanoid	1	1.050	209	1.000	Inparanoid score	I3689
Isobase	1	0.950	-	0	Normalized mean entropy	S381
OMA	1	1.010	-	-		QHG54028
OrthoDB	1	1.010	-	-		D1587140at2759
OrthoFinder	1	1.000	-	-		FOG0003438
OrthoInspector	1	1.000	-	-		oto88802
orthoMCL	1	0.900	-	-		OOG6_102466
Panther	1	1.100	-	-	LDO	PTHR11210
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1071
SonicParanoid	1	1.000	-	-		X2333
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	17	16.750