Protein Alignment su(sable) and zc3h4

DIOPT Version :10

• Sequence 1: NP_476754.1
• Gene: su(sable) / 31012
• FlyBaseID: FBgn0003575
• Length: 1325
• Species: Drosophila melanogaster
• Sequence 2: XP_005157662.1
• Gene: zc3h4 / 557823
• ZFINID: ZDB-GENE-100330-1
• Length: 1340
• Species: Danio rerio
• Alignment Length: 1399
• Identity: 288/1399 - (20%)
• Similarity: 442/1399 - (31%)
• Gaps: 584/1399 - (41%)

  Fly     5 LADEPLIDLEEDLEDGEIDDD-EEDEQQSSKIQVQKKTFVGDDDVQFVGVEAKNQNDDEDVVYVG 68
            |.||...|.|  ||:||::|| .|.|..|.::.                       |.:|
Zfish    23 LTDERQEDGE--LEEGELEDDGGEAEVPSGEVA-----------------------DPQD----- 57

  Fly    69 PSTDAVCLQNSNSTKSKKPRPLEDDHASSIELAIANALKKKGIEPPMPRMRSSNQDTSDQSLEGS 133
                             |||..::.|||                      .|::::.|.:
Zfish    58 -----------------KPRHSKERHAS----------------------ESNDEEKSHR----- 78

  Fly   134 GEGLATANPLLQSTRSSRRRKRKKERERE--------QKKDKEQQNRSRRDE-NDVSVVPGGVED 189
                             ||||||:|||||        ::|.|.::::|..|| :|.|       |
Zfish    79 -----------------RRRKRKREREREKEKRRAKKKRKSKHKRHQSSSDEYSDYS-------D 119

  Fly   190 MDEY---EMMNVRGGSPP------------PGGAAPPLSSCG-------QRFSG----------- 221
            ..:|   |....|..|||            |.|...|:|..|       |.:.|
Zfish   120 ESDYSPSEKRKYREYSPPYPPTSQGGYSSAPSGHGGPMSKKGGYMKIDKQGYGGYDDYEEETYEG 184

  Fly   222 ------ADWDMDD------------------------------GSAATGAAGLGAGGG------- 243
                  .|.|.||                              |....|..|.|..||
Zfish   185 EDDEDMGDDDYDDFAKELNQYRKAKEVGGPRGRGGKNRMKNLRGRGRGGMRGRGGRGGGRGRGRG 249

  Fly   244 --GGYN---------------------SHSSYDSYSDEETNGPGLMNQRRRTRRDNEKEHQRGVN 285
              ||.|                     ....||.||.|       :||.|:|:       .||..
Zfish   250 KMGGENDDGDGMYGEDMEYGDDDYDNMGDDDYDDYSKE-------LNQYRKTK-------DRGRG 300

  Fly   286 NRKRRDRDRLEGGLAGSGSKRNR-RDSGEGGGG----------------------------GQEK 321
            .:..|.|.|   |..|.|..|.| |:.|.|.||                            |.||
Zfish   301 GKGGRGRGR---GKGGRGMNRGRGRNRGRGRGGDQGPDDDNSGDKDMDGSGPPRRNDQEKHGPEK 362

  Fly   322 MGG-------------------SNRVE-PRKLELCKFYLMDCCAKRDKCSYMHKEFPCKYYYLGM 366
            .|.                   |:.:| |:|.||||||:...||:.:.|.|||.:||||.::...
Zfish   363 KGKAICKYYIEGRCTWGDHCNFSHDIELPKKKELCKFYITGFCARAENCPYMHGDFPCKLFHTTG 427

  Fly   367 DCYAGDDCLFYHGEPLSEQLRNVLLKHMETAPKEILGDFKRISRDIAIVQMTRRHEQLCDQLNRE 431
            :|..|::|:|.| :.|:|..:.:|       .|.:..|.:..:.|          |:..::|.::
Zfish   428 NCVNGEECMFSH-DSLTEDTQELL-------DKMLAEDAEAGAED----------EKEVEELKKQ 474

  Fly   432 NTWNSI-----GCGLMGK-------RQDHQMQQQQQQLQHQQLQQQQEQQ--------------- 469
            .. |.:     |.||:..       .....|:.......|..:.......
Zfish   475 GI-NPLPKPPPGVGLLPTPPRPSPGDSSTPMEFGMPSAPHGNIPPSGPPAPGPGVGPVPGPGPGP 538

  Fly   470 ---------QTQQQAAADGGG------------------C-------IPSLLDMVINPPLSENKR 500
                     ........|||.                  |       ||||.::|:.|
Zfish   539 GPGPGIGPCPVPPPPCTDGGTFQGPPPTGPPPPMGPPPVCGGNAGKKIPSLFEIVVKP------- 596

  Fly   501 KSRWTEKMG------AKAAAGAAGSSERDSTSPDAKP--LPP---HLDLANLSHVLSAENMAKLN 554
            ..:..:|:|      |.|:||.||........|.|.|  .||   |:.... .|        :..
Zfish   597 TGQLAQKLGVRGPVPANASAGTAGPQGPPPGPPGAPPPRFPPPPGHMGPGG-PH--------ERP 652

  Fly   555 KLGITNLEQMLQVPFGQLTEAGLTLVEIGEIQRKAEDAKPQTQAELESSTPPSKRETEANNSNSK 619
            .:|.:|:.|            |...:..|         .|..|..::...||:.........::.
Zfish   653 PMGPSNMNQ------------GPPSMGTG---------PPMMQNFVQGEGPPNPGMMSPGAGSAG 696

  Fly   620 SNGLIMVDYTQYLKDAHVSFSGNDPLDDDRDDDEQLIIDDGNDSTAEEDQQPKKAKAPPAATHES 684
            :|  ...::.|..:...:..||       ||.|....:..||.:    ||.|        ..|.|
Zfish   697 NN--FYDNFYQQQQAMSIDGSG-------RDCDNFQGMGGGNFN----DQSP--------GNHNS 740

  Fly   685 STEEAPL---PS---VFDLPSFM------------NNMLGQGSSARQLLPASATSPNQENAHLPG 731
            .:.|:..   ||   ...:|.|:            .........||:|.....|....|     |
Zfish   741 GSMESGANVGPSNQTGMAVPDFLPPAQRVLFMRLQQKQQEDEERARRLADGGGTERENE-----G 800

  Fly   732 GDQSTHKSA--PIGGGTSTNVLGRILFGDKQ-----------SDPEARAAFYRDIIRNPFKAHSG 783
            ||.:...|:  ..|||:.|::| :.|....|           |||..:.:       .|..|.|.
Zfish   801 GDSANWYSSEDEDGGGSVTSIL-KTLRQQTQNQGPAKPDGAPSDPRLQKS-------QPTPAPSR 857

  Fly   784 DGDVDSSNE-----NSNSN-----SHSLTPTPTPEPGSQSPKPEDH---DQDMPELPVIAPALPP 835
            ..|...:.:     |::|:     |.||:|||:      .|:...|   ....||.|::....|.
Zfish   858 PADPRLARDPRLSRNTDSSQAPEASSSLSPTPS------DPRLARHAAAHASKPEPPLVYKPPPL 916

  Fly   836 TTPSLYVRRSMYDFDPVKEQEHGRQELLTEEKEQYQRDTDMRLPFEPMKHYM---PATEIDAAIF 897
            |.|:            ..|:|.|         |:..||..:.:|.:|:....   |.:::..  |
Zfish   917 TAPA------------SNEEEEG---------ERMLRDKPVPIPLDPLMGMALRDPRSQLQQ--F 958

  Fly   898 SHTPIRWQLHEVTIEESSYAQIRASALHKE--------QRELR------------DPRMRRILGL 942
            ||..     .:|.:::.|::  :|.....|        :::|.            |||:.|
Zfish   959 SHIK-----KDVVLQKPSFS--KAVLWSPEDLIPIPIPKQDLLPLPPGIPPVTTIDPRLSR---- 1012

  Fly   943 PETPDNSGPLGSVPIMGPSSFSVDNIARCATTIASPDLETAVR-----DSTPSSP---------- 992
            .:.|.:|..|....:..|:.....|    .::.:.||.|...|     :::.|||
Zfish  1013 TQPPHHSSILPPTVVPPPAPVEQSN----QSSSSLPDFELLSRILKTVNASSSSPVQGASTGISS 1073

  Fly   993 PPSVVNLPSMSVPPPSMRVPP--PNIQVEKPTVRTD-----PRRDPRRAVLQAPTKGASTANTTA 1050
            ||||.:  ...:.|...|..|  |.:|.:|..::|.     |:..|..:.|..|    |::.|.|
Zfish  1074 PPSVSS--EKPIDPRMARKTPADPRLQPQKSALKTTSEPLVPQGSPPTSSLSPP----SSSPTIA 1132

  Fly  1051 PN-----ASGGSKQISEIRSLLQVSNWYNNLGTN 1079
            |.     ::|||     :||:...|...::.||:
Zfish  1133 PYDPRLLSAGGS-----VRSVGSASVGSSSGGTS 1161

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
su(sable)	NP_476754.1	None
zc3h4	XP_005157662.1	zf-CCCH_4	367..387	CDD:465626	1/19 (5%)
		ZnF_C3H1	393..417	CDD:214632	13/23 (57%)
		PTZ00449	<789..1111	CDD:185628	80/380 (21%)