Protein Alignment Dredd and CASP7

DIOPT Version :10

• Sequence 1: NP_477249.3
• Gene: Dredd / 31011
• FlyBaseID: FBgn0020381
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_001253986.1
• Gene: CASP7 / 840
• HGNCID: 1508
• Length: 388
• Species: Homo sapiens
• Alignment Length: 335
• Identity: 86/335 - (25%)
• Similarity: 141/335 - (42%)
• Gaps: 61/335 - (18%)

  Fly   192 QLLVGHLKSNGLQAQANLLKDTIISNAPE-------PDAAGTAAMAVKQEIESDNQQSYCSTQID 249
            |::...|||.||:.|...::..:....|.       || :||.....|::         .:..:.
Human    77 QMIRAVLKSRGLRIQQMKIQWMLSQTGPRLYRPSSAPD-SGTLYFTSKKK---------KNVTMR 131

  Fly   250 ALKLTR------------ENAGIALIINQQKFHRNVSRDNMKFLSPDPLRRRDGTDVDKERLIEV 302
            ::|.||            |..|..:|||.:.|.:...           :..|:|||.|.|.|.:.
Human   132 SIKTTRDRVPTYQYNMNFEKLGKCIIINNKNFDKVTG-----------MGVRNGTDKDAEALFKC 185

  Fly   303 FSSMGYNVEAYDNVDHMGIIERIRSACDRSLVRDS-LVVFILSHGFEEAVYASNSIAMKITDIED 366
            |.|:|::|..|::.....:.:.::.|.:......: ....:||||.|..:|..:.    :|.|:|
Human   186 FRSLGFDVIVYNDCSCAKMQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDG----VTPIKD 246

  Fly   367 LLCSY-----DTLYYKPKLLIIQACQEKLVHKKKPNELFRIDVTTVSPDQHI----DMLRAMSTV 422
            |...:     .||..||||..||||:...:......:...|:.|..:|...|    |.|.|.|||
Human   247 LTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTV 311

  Fly   423 NGYAALRHTQTGSWFIGSLCDAIDRRSASEHIADILTIVTNEVSKKRGS-------NDESMVPNV 480
            .||.:.|....||||:.:||..::.......|..|||.|.:.|::...|       :::..:|.|
Human   312 PGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCV 376

  Fly   481 KSTFRQHVYF 490
            .|...:.:||
Human   377 VSMLTKELYF 386

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dredd	NP_477249.3	CASc	252..492	CDD:444667	73/268 (27%)
CASP7	NP_001253986.1	CASc	145..386	CDD:237997	68/255 (27%)