Protein Alignment Dredd and CASP5

DIOPT Version :9

• Sequence 1: NP_477249.3
• Gene: Dredd / 31011
• FlyBaseID: FBgn0020381
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_001129584.1
• Gene: CASP5 / 838
• HGNCID: 1506
• Length: 447
• Species: Homo sapiens
• Alignment Length: 351
• Identity: 77/351 - (21%)
• Similarity: 133/351 - (37%)
• Gaps: 84/351 - (23%)

  Fly   193 LLVGHLKSNGL------QAQANL------LKDTIISNAPEPDAAGTAAMAVKQEIESDNQQSYCS 245
            :||..|:.|.:      |...|:      :|..:...|..|::|           ||.|....|.
Human   127 ILVDSLRKNRVAHQMFTQTLLNMDQKITSVKPLLQIEAGPPESA-----------ESTNILKLCP 180

  Fly   246 TQIDALKLTRENAGIALIINQQKFHRNVSR--DNMKFLSPDPLRRRDGTDVDKERLIEVFSSMGY 308
            .: :.|:|.::|......|.:::..|.::.  .|.||   |.|..|:|...|...:..:...:||
Human   181 RE-EFLRLCKKNHDEIYPIKKREDRRRLALIICNTKF---DHLPARNGAHYDIVGMKRLLQGLGY 241

  Fly   309 NVEAYDNVDHMGIIERIRSACDRSLV-------RDSLVVFILSHGFEEAVYASNSIAMKITDIED 366
            .|     ||...:..|...:..|:..       .||..:.::|||..|.:..:.....|    .|
Human   242 TV-----VDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAHKKKK----PD 297

  Fly   367 LLCSYDTLYY------------KPKLLIIQACQ-EK--------------LVHKKKPNELFRIDV 404
            :|. |||::.            |||::|:|||: ||              |:..:....|....|
Human   298 VLL-YDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQSSENLEADSV 361

  Fly   405 TTVSPDQHIDMLRAMSTVNGYAALRHTQTGSWFIGSLCDAIDRRSASEHIADILTIVTN--EVSK 467
            ..:..::  |.:...|:.....:.|....||.||..|.....:.|...|:.:|...|..  ||.:
Human   362 CKIHEEK--DFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLMEIFRKVQKSFEVPQ 424

  Fly   468 KRGSNDESMVPNV-KSTFRQHVY-FP 491
            .:     :.:|.: ::|..:..| ||
Human   425 AK-----AQMPTIERATLTRDFYLFP 445

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dredd	NP_477249.3	CASc	252..492	CDD:294037	62/280 (22%)
CASP5	NP_001129584.1	DD	76..155	CDD:301326	6/27 (22%)
		CASc	196..445	CDD:214521	58/268 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3573
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10454
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.910