Protein Alignment Dredd and Casp2

DIOPT Version :10

• Sequence 1: NP_477249.3
• Gene: Dredd / 31011
• FlyBaseID: FBgn0020381
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_071967.2
• Gene: Casp2 / 64314
• RGDID: 69274
• Length: 452
• Species: Rattus norvegicus
• Alignment Length: 489
• Identity: 116/489 - (23%)
• Similarity: 192/489 - (39%)
• Gaps: 139/489 - (28%)

  Fly    94 LRRLGFCWQELRMHYLPHIAGITLHVHP-----LLKSLYRMCEEL-------SLVQSGRLLLDVR 146
            |.|.|....:.|...|. :.|    :||     |.|:...:.::|       .|::...:.|::|
  Rat    12 LHRKGLMAADRRSRILA-VCG----MHPDHQETLKKNRVVLAKQLLLSELLEHLLEKDIITLEMR 71

  Fly   147 EKVESQ-------------------QAGD----PLRFYDPAYLEIFLLDWLTRRSIKLGDINAAG 188
            |.::::                   ||.|    .||.....:||..||..|
  Rat    72 ELIQAKGGSFSQNVELLNLLPKRGPQAFDAFCEALRETRQGHLEDLLLTTL-------------- 122

  Fly   189 SDVQLLVGHL-------------KSNGLQAQANLLKDTIISNAPEPDAAGTAAMAVKQEIESDNQ 240
            ||:|.::..|             :|.....|:.|..||:..:....|  |...:.||.......|
  Rat   123 SDIQHILPPLSCDYDSSLPFSVCESCPPHKQSRLSTDTMEHSLDNGD--GPPCLQVKPCTPEFYQ 185

  Fly   241 QSYCSTQIDALKLTRENAGIALIINQQKFHRNVSRDNMKFLSPDPLRRRDGTDVDKERLIEVFSS 305
            ..|   |: |.:|..:..|:||:::           |:.|.....|..|.|.|||...|:.:|..
  Rat   186 AHY---QL-AYRLQSQPRGLALVMS-----------NVHFTGEKDLEFRSGGDVDHTTLVTLFKL 235

  Fly   306 MGYNVEAYDNVDHMGIIERIRSACD--RSLVRDSLVVFILSHGFEEAVYASNSIAMKITDIEDLL 368
            :||||....:.....:.|::::...  ...|.||.:|.:||||.|..:|..:.   |:..::::.
  Rat   236 LGYNVHVLYDQTAQEMQEKLQNFAQLPAHRVTDSCIVALLSHGVEGGIYGVDG---KLLQLQEVF 297

  Fly   369 CSYD-----TLYYKPKLLIIQAC-----------QEKLVHKKKP---------NELFRIDVTTVS 408
            ..:|     :|..|||:..||||           |:...|.:.|         .||.::.:.|.|
  Rat   298 RLFDNANCPSLQNKPKMFFIQACRGDETDRGVDQQDGKNHAQSPGCEESDAGKEELMKMRLPTRS 362

  Fly   409 PDQHIDMLRAMSTVNGYAALRHTQTGSWFIGSLCDAIDRRSASEHIADILTIVTNEVSKKRGSND 473
                 ||:...:.:.|.||:|:|:.|||:|.:|......|:...|:||:| :..|.:.|:|
  Rat   363 -----DMICGYACLKGNAAMRNTKRGSWYIEALTQVFSERACDMHVADML-VKVNALIKER---- 417

  Fly   474 ESMVPNVK-----------STFRQHVY----FPP 492
            |...|..:           ||..|.:|    :||
  Rat   418 EGYAPGTEFHRCKEMSEYCSTLCQQLYLFPGYPP 451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dredd	NP_477249.3	CASc	252..492	CDD:444667	72/281 (26%)
Casp2	NP_071967.2	CASc	192..447	CDD:214521	72/278 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	327..349		3/21 (14%)
		CARD_CASP2	32..118	CDD:260040	16/85 (19%)