Protein Alignment Dredd and casp10

DIOPT Version :9

• Sequence 1: NP_477249.3
• Gene: Dredd / 31011
• FlyBaseID: FBgn0020381
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: XP_685430.4
• Gene: casp10 / 557302
• ZFINID: ZDB-GENE-070608-2
• Length: 520
• Species: Danio rerio
• Alignment Length: 550
• Identity: 127/550 - (23%)
• Similarity: 218/550 - (39%)
• Gaps: 122/550 - (22%)

  Fly    10 LDTIDQNDLIYV------ERDMNFAQKVGLCF-------LLYGDDHSDATYILQKLLAMTRSD-- 59
            |...:..||:::      .||:|........|       ||..:|.|    :|.:||::|:..
Zfish    22 LSADELQDLLFLCSDLLCSRDLNTVSSGRQLFTLLQNQDLLSLEDPS----LLIELLSITKRTRL 82

  Fly    60 --FPQSDLLIKFA---------KSRPETWRRHLVEALCIIGARKVLRRLGFCWQELR-MHYLPHI 112
              ..|||..::.:         :.|...:|:.|.|.           ....|.|:|: :.:|
Zfish    83 MRSLQSDACMQTSGTADQPLQQQQRISRYRQFLYEL-----------SESICDQDLKNIKFL--- 133

  Fly   113 AGITLHVHPLLKSLYR--MCEELSLVQ----------SGRLLLDVREKVESQ---QAGDPLRFYD 162
                     |:|:|.|  :.:.|:|:|          .|...|||.:::.:.   ..|..:..|.
Zfish   134 ---------LMKTLSRKKLEQNLTLLQLFLEMEKEDLLGENNLDVLQRIFADIYPALGRKINQYK 189

  Fly   163 PAYLEIFLLDWLTRRSIKLGDINAAG---SDVQLLVGHLKSNGLQAQANLLKDTIISNAPEPDAA 224
            ...|....:...|.....:.|:.:|.   |.|:::...:....|...|:....   .|:...|:.
Zfish   190 EENLNGVFIAQETEGISSIADLPSAQTSLSSVEMIDREMDEITLNENASGFSG---DNSQHSDSV 251

  Fly   225 GTAAMAVKQEIESDNQQSYCSTQIDALKLTRENAGIALIINQQKFHRNVSRDNMKFLSPDPLRRR 289
            .:..::     ||.......::.::..::..|..|:.||||...|            |......|
Zfish   252 NSGIIS-----ESSEMPQIENSMVEQYEMKGERRGVCLIINNYDF------------SACGWLNR 299

  Fly   290 DGTDVDKERLIEVFSSMGYNVEAYDNVDHMGIIERIRSACDRSLVR-DSLVVFILSHGFEEAVYA 353
            :|||:|.:.|.:||..:|:.:....:.....|::.:.....:...: |.:|..|||||....:..
Zfish   300 EGTDIDHDSLRDVFEWLGFEILTRRDCTGDQILQALMDLSTQDHTQADCVVCCILSHGRLNDIIG 364

  Fly   354 SNSIAMKITDIEDLL----CSYDTLYYKPKLLIIQACQEKLVHKKKPNELFRIDVTTVSPDQHI- 413
            .:..|:...::.:.|    ||  :||.||||..||||:.....:....:.|..|...::.|..:
Zfish   365 VDGKAVPFKELMETLSPFRCS--SLYQKPKLFFIQACRGTQNQRAVFPQTFTEDEDVLASDAGVP 427

  Fly   414 --------DMLRAMSTVNGYAALRHTQTGSWFIGSLCD----AIDRRSASEHIADILTIVTNEVS 466
                    |.|.|||||..||:.|....|:|||.||||    .:.|   ...:..|||.|..:||
Zfish   428 RDSIPEMADYLMAMSTVPWYASYRDKSKGTWFIQSLCDNLRLLVPR---GNDLLSILTKVNADVS 489

  Fly   467 KKRGSNDES----MVPNVKSTFRQHVYFPP 492
            ||   :|:|    .:|..:.:..:.|.|||
Zfish   490 KK---SDKSGLKKQMPQPEFSLTRTVVFPP 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dredd	NP_477249.3	CASc	252..492	CDD:294037	74/261 (28%)
casp10	XP_685430.4	DED_Caspase_8_10_r1	11..87	CDD:260059	15/68 (22%)
		DED_Caspase_8_10_r2	108..190	CDD:260042	20/104 (19%)
		DUF4603	<200..>256	CDD:292020	9/58 (16%)
		CASc	273..515	CDD:237997	73/261 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170578012
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3573
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	4	3.700