Protein Alignment Dredd and Casp1

DIOPT Version :10

• Sequence 1: NP_477249.3
• Gene: Dredd / 31011
• FlyBaseID: FBgn0020381
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_036894.3
• Gene: Casp1 / 25166
• RGDID: 2274
• Length: 402
• Species: Rattus norvegicus
• Alignment Length: 375
• Identity: 88/375 - (23%)
• Similarity: 148/375 - (39%)
• Gaps: 103/375 - (27%)

  Fly   142 LLD--VREKVESQQAGDPLRFYDPAYLEIF--LLDWLTRRSIKLGDINAAGSDVQLLVGHLKSNG 202
            |||  :.::|.:|:..|.::..:...:|..  |.|.:|::..:..         |:.:.::.:..
  Rat    25 LLDELLEKRVLNQEEMDTIKLANITVMEKARDLCDHVTKKGPRAS---------QMFITYICNED 80

  Fly   203 ------LQAQANLLKDTII----SNAPEPDAAGTAAMAVKQEIESD--------NQQSYCSTQID 249
                  |:.|:....:|:.    |....|.::.|     |:::..:        ....:|..:|
  Rat    81 CYLAEILELQSGPSAETVFVTEDSKGGHPFSSET-----KEKLNKEGGAFPGPSGSLKFCPLEI- 139

  Fly   250 ALKLTREN-------------AGIALIINQQKFHRNVSRDNMKFLSPDPLRRRDGTDVDKERLIE 301
            |.||.:||             ..:||||....|..              |.||.|.|||...:..
  Rat   140 AQKLWKENHSEIYPIMKTPTRTRLALIICNTDFQH--------------LSRRVGADVDLREMKL 190

  Fly   302 VFSSMGYNVEAYDNVDHMGIIERIR--SACDRSLVRDSLVVFILSHGFEEAVYA---SNSIA--M 359
            :...:||.|:..:|:..:.:.:.::  :||......||..:..:|||.:|.:..   ||.:|  :
  Rat   191 LLQDLGYTVKVKENLTALEMTKELKEFAACPEHKTSDSTFLVFMSHGLQEGICGITYSNEVADIL 255

  Fly   360 KITDI----EDLLCSYDTLYYKPKLLIIQACQ-EK----LVHKKKPN--ELFRIDVTTVSPDQ-- 411
            |:..|    ..|.|  .:|..|||::|||||: ||    |:.....|  |.|..|  .:..|.
  Rat   256 KVDTIFQMMNTLKC--PSLKDKPKVIIIQACRGEKQGVVLLKDSVGNSEEGFLTD--AIFEDDGI 316

  Fly   412 ---HI--DMLRAMSTVNGYAALRHTQTGSWFIGSL----------CDAID 446
               ||  |.:...|:.....:.||...||.||.||          ||..|
  Rat   317 KKAHIEKDFIAFCSSTPDNVSWRHPVQGSLFIESLIKHMKEYAWSCDLED 366

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dredd	NP_477249.3	CASc	252..492	CDD:444667	67/243 (28%)
Casp1	NP_036894.3	CARD_CASP1-like	6..87	CDD:260036	11/70 (16%)
		CASc	152..400	CDD:214521	63/233 (27%)