Protein Alignment Dredd and Casp12

DIOPT Version :10

• Sequence 1: NP_477249.3
• Gene: Dredd / 31011
• FlyBaseID: FBgn0020381
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_569106.1
• Gene: Casp12 / 156117
• RGDID: 621758
• Length: 420
• Species: Rattus norvegicus
• Alignment Length: 341
• Identity: 67/341 - (19%)
• Similarity: 114/341 - (33%)
• Gaps: 101/341 - (29%)

  Fly   192 QLLVGHLKSNGLQAQANLLKD---TIISNAPEPDAAGTAAMAVKQEIESDN-------------Q 240
            ::..||:.::..|.......|   ..:.....|.:|..:...|:.|....|             .
  Rat    71 KIFAGHIANSDKQLSLQFPSDDEEDELQKMFTPSSASESRGKVEDEEMEVNVGVAHASHLMLTVP 135

  Fly   241 QSYCSTQI-DALKL-------------------TRENAG---IALIINQQKFHRNVSRDNMKFLS 282
            |...||:: |:|||                   ..|..|   :||||..:||
  Rat   136 QGIQSTEVQDSLKLCSRDWFCTMKTERAEEIYPVMEKEGRTRLALIICNKKF------------- 187

  Fly   283 PDPLRRRDGTDVDKERLIEVFSSMGYNVEAYDNVDHMGIIERIRSACDR--SLVRDSLVVFILSH 345
             |.|..||..:.|...:.|:..::||:|...:|:....:...:.....|  ....||..:..:||
  Rat   188 -DYLFDRDDAETDILNMKELLQNLGYSVVIKENLTAQEMETELMKFAGRPEHQSSDSTFLVFMSH 251

  Fly   346 GFEEAVYASNSIAMKITDIEDLLCSYDTLY------------YKPKLLIIQAC------------ 386
            |..|.:........|...:.|     ||::            .|||:||:|||
  Rat   252 GILEGICGVKHRNKKPDVLHD-----DTIFTIFNNSNCPSLRNKPKILIMQACRGRHTGTIWVST 311

  Fly   387 ----------QEKLVHKKKPNELFRIDVTTVSPDQHIDMLRAMSTVNGYAALRHTQTGSWFIGSL 441
                      :|.::..:..|.:.:..|.|       |.:...|:.....:.:..::||.||..|
  Rat   312 SKGIATADTDEECVLSHRWNNSITKAHVET-------DFIAFKSSTPHNISWKVGKSGSLFISKL 369

  Fly   442 CDAIDRRSASEHIADI 457
            .|...:.....|:.:|
  Rat   370 IDCFKKYCWCYHLEEI 385

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dredd	NP_477249.3	CASc	252..492	CDD:444667	53/264 (20%)
Casp12	NP_569106.1	CARD_CASP1-like	6..88	CDD:260036	3/16 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	93..115		3/21 (14%)
		CASc	167..418	CDD:214521	51/245 (21%)