Protein Alignment Dredd and Casp12

DIOPT Version :9

• Sequence 1: NP_477249.3
• Gene: Dredd / 31011
• FlyBaseID: FBgn0020381
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: XP_036010474.1
• Gene: Casp12 / 12364
• MGIID: 1312922
• Length: 425
• Species: Mus musculus
• Alignment Length: 409
• Identity: 81/409 - (19%)
• Similarity: 142/409 - (34%)
• Gaps: 129/409 - (31%)

  Fly   179 IKLGD-----INAAGSDVQ-----------LLVGHLKSNGLQAQANLLKDTIISNAPEPDAAGTA 227
            :|:|:     :|.|.:.|:           :..||:.::  |.|.:|.......:.|:.....::
Mouse    48 LKIGESASFILNKAENLVENFLEKTDMAGKIFAGHIANS--QEQLSLQFSNDEDDGPQKICTPSS 110

  Fly   228 AMAVKQEIESDNQQ-----------------SYCSTQI-DALKL-------------------TR 255
            ....|:::|.|..:                 ...|::: |.|||                   ..
Mouse   111 PSESKRKVEDDEMEVNAGLAHESHLMLTAPHGLQSSEVQDTLKLCPRDQFCKIKTERAKEIYPVM 175

  Fly   256 ENAG---IALIINQQKFHRNVSRDNMKFLSPDPLRRRDGTDVDKERLIEVFSSMGYNVEAYDNVD 317
            |..|   :||||..:||              |.|..||..|.|...:.|:..::||:|...:|:.
Mouse   176 EKEGRTRLALIICNKKF--------------DYLFDRDNADTDILNMQELLENLGYSVVLKENLT 226

  Fly   318 HMGIIERIRSACDR--SLVRDSLVVFILSHGFEEAVYASNSIAMKITDIEDLLCSYDTLY----- 375
            ...:...:.....|  ....||..:..:|||..|.:........|...:.|     ||::
Mouse   227 AQEMETELMQFAGRPEHQSSDSTFLVFMSHGILEGICGVKHRNKKPDVLHD-----DTIFKIFNN 286

  Fly   376 -------YKPKLLIIQAC----------------------QEKLVHKKKPNELFRIDVTTVSPDQ 411
                   .|||:||:|||                      :|:::..|..|.:.:..|.|
Mouse   287 SNCRSLRNKPKILIMQACRGRYNGTIWVSTNKGIATADTDEERVLSCKWNNSITKAHVET----- 346

  Fly   412 HIDMLRAMSTVNGYAALRHTQTGSWFIGSLCDAIDRRSASEHIADILTIVTN--EVSKKRGSNDE 474
              |.:...|:.....:.:..:|||.||..|.|...:.....|:.:|...|.:  ||     ..:.
Mouse   347 --DFIAFKSSTPHNISWKVGKTGSLFISKLIDCFKKYCWCYHLEEIFRKVQHSFEV-----PGEL 404

  Fly   475 SMVPNVK--STFRQHVYFP 491
            :.:|.::  |..|....||
Mouse   405 TQMPTIERVSMTRYFYLFP 423

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dredd	NP_477249.3	CASc	252..492	CDD:294037	64/302 (21%)
Casp12	XP_036010474.1	CARD_CASP1-like	12..94	CDD:260036	10/47 (21%)
		CASc	172..423	CDD:214521	60/281 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3573
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10454
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910