Protein Alignment Dredd and Casp1

DIOPT Version :9

• Sequence 1: NP_477249.3
• Gene: Dredd / 31011
• FlyBaseID: FBgn0020381
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_033937.2
• Gene: Casp1 / 12362
• MGIID: 96544
• Length: 402
• Species: Mus musculus
• Alignment Length: 367
• Identity: 83/367 - (22%)
• Similarity: 134/367 - (36%)
• Gaps: 115/367 - (31%)

  Fly   170 LLDWLTRR---------SIKLGDINAAGSDVQLLVGHLKSNGLQAQANLL-----KDTIISNAPE 220
            |||.|..:         .|||.:|.|. ...:.|..|:...|.||....:     :|..::...|
Mouse    25 LLDELLEKRVLNQEEMDKIKLANITAM-DKARDLCDHVSKKGPQASQIFITYICNEDCYLAGILE 88

  Fly   221 PDAAGTAAMAVKQE------------IESDNQQ-----------SYCSTQIDALKLTRENAG--- 259
            ..:|.:|...|..|            .|..|::           .:|..: .|.||.:||..
Mouse    89 LQSAPSAETFVATEDSKGGHPSSSETKEEQNKEDGTFPGLTGTLKFCPLE-KAQKLWKENPSEIY 152

  Fly   260 ----------IALIINQQKFHRNVSRDNMKFLSPDPLRRRDGTDVDKERLIEVFSSMGYNVEAYD 314
                      :||||...:|         :.|||     |.|..||...:..:...:||.|:..:
Mouse   153 PIMNTTTRTRLALIICNTEF---------QHLSP-----RVGAQVDLREMKLLLEDLGYTVKVKE 203

  Fly   315 NVDHMGIIERIR--SACDRSLVRDSLVVFILSHGFEEAVYASNSIAMKITDIEDLLCSYDTLYY- 376
            |:..:.:::.::  :||......||..:..:|||.:|.: ...:.:.:::||    ...||::.
Mouse   204 NLTALEMVKEVKEFAACPEHKTSDSTFLVFMSHGIQEGI-CGTTYSNEVSDI----LKVDTIFQM 263

  Fly   377 -----------KPKLLIIQACQEKLVHKKKPNELFRIDVTTVSPD--------------QHI--D 414
                       |||::|||||:    .:|:...|.:..|.....|              .||  |
Mouse   264 MNTLKCPSLKDKPKVIIIQACR----GEKQGVVLLKDSVRDSEEDFLTDAIFEDDGIKKAHIEKD 324

  Fly   415 MLRAMSTVNGYAALRHTQTGSWFIGSL----------CDAID 446
            .:...|:.....:.||...||.||.||          ||..|
Mouse   325 FIAFCSSTPDNVSWRHPVRGSLFIESLIKHMKEYAWSCDLED 366

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dredd	NP_477249.3	CASc	252..492	CDD:294037	59/248 (24%)
Casp1	NP_033937.2	CARD_CASP1-like	6..87	CDD:260036	15/62 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	98..125		4/26 (15%)
		CASc	152..400	CDD:214521	55/238 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3573
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10454
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910