Protein Alignment Dredd and Casp4

DIOPT Version :10

• Sequence 1: NP_477249.3
• Gene: Dredd / 31011
• FlyBaseID: FBgn0020381
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_446188.2
• Gene: Casp4 / 114555
• RGDID: 621757
• Length: 373
• Species: Rattus norvegicus
• Alignment Length: 397
• Identity: 91/397 - (22%)
• Similarity: 154/397 - (38%)
• Gaps: 83/397 - (20%)

  Fly   150 ESQQAGDPLRFYDPAYLEIFLLDWLTR----RSIKLGD------INAAGSDVQ-LLVGHLKSNGL 203
            |:.....||:..:....| ||.::|.:    ..:||.:      .||..||.: :.|..||....
  Rat     3 ENNHPDKPLKVLEELGKE-FLTEYLEKLVQSNVLKLKEEEKQKFNNAERSDKRWVFVDVLKRKHN 66

  Fly   204 QAQANLLKDTIISNAPEPDAAGTAAMAVKQEIESDNQQSYCST------------QIDALKLTRE 256
            |....||:..:  |.......|.|.:.:::..||.:....||:            :|..:|.|..
  Rat    67 QVGKMLLQTFL--NVDSGSHHGEANLEMEEPEESVDTLKLCSSEEFTRLCREKKQEIYPIKETNG 129

  Fly   257 NAGIALIINQQKFHRNVSRDNMKFLSPDPLRRRDGTDVDKERLIEVFSSMGYNVEAYDNVDHMGI 321
            ....||||...:|         |.||     .|.|.::|...:..:...:||:|...:.:...|:
  Rat   130 RTRKALIICNTEF---------KHLS-----LRYGANIDISGMKGLLEELGYDVVVKEELTAEGM 180

  Fly   322 IERIR--SACDRSLVRDSLVVFILSHGFEEAVYASNSIAMKITDIEDLLCSYDTLYY-------- 376
            ...::  :|.......||..:.::|||..:.:..:    |......|:|. |||:|.
  Rat   181 ESEMKDFAALSEHQTSDSTFLVLMSHGTLQGLCGT----MHSEATPDVLL-YDTIYQIFNNCHCP 240

  Fly   377 ----KPKLLIIQAC-----------QEKLVHKKKPNELFR---IDVTTVSPDQHI--DMLRAMST 421
                |||::|:|||           :....|..:..:|.|   .|...:|   |:  |.:...||
  Rat   241 GLRDKPKVIIVQACRGGNPGEVWIRESSGAHSYRAVDLPRNMEADAVRMS---HVEKDFIALYST 302

  Fly   422 VNGYAALRHTQTGSWFIGSLCDAIDRRSASEHIADILTIVTNEVSKKRGSNDESMVPNV-KSTFR 485
            ...:.:.|....||:||..|.......:.|.|:.||...|.....|   ::..|.:|.: ::|..
  Rat   303 TPHHLSYRDKTRGSYFISKLISCFRIHACSCHLFDIFLKVQQSFEK---ASINSQMPTIDRATLT 364

  Fly   486 QHVY-FP 491
            ::.| ||
  Rat   365 RYFYLFP 371

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dredd	NP_477249.3	CASc	252..492	CDD:444667	64/272 (24%)
Casp4	NP_446188.2	CARD_CASP1-like	5..85	CDD:260036	19/82 (23%)
		CASc	122..371	CDD:214521	62/273 (23%)