Protein Alignment Dredd and CASP12

DIOPT Version :9

• Sequence 1: NP_477249.3
• Gene: Dredd / 31011
• FlyBaseID: FBgn0020381
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_001177945.2
• Gene: CASP12 / 100506742
• HGNCID: 19004
• Length: 341
• Species: Homo sapiens
• Alignment Length: 332
• Identity: 67/332 - (20%)
• Similarity: 113/332 - (34%)
• Gaps: 97/332 - (29%)

  Fly   214 IISNAPE--PDAAGTAAMAVK--------------QEIESDNQQSYCSTQIDALKLTRENAGIAL 262
            ::|||..  .|...||.:|.|              .:|.||.:              ||.....|
Human    51 VVSNAENLVDDITETAQIAGKIFREHLWNSKKQLSSDISSDGE--------------REANMPGL 101

  Fly   263 IINQQKFHRNVSRDNMKFLSPDPLRRRDGTDVDKERLIEVFSSMGYNVEAYDNVDHMGIIERIR- 326
            .|..::|:.              |..|:|:::|...:.::..::||:|...:|:....:...:|
Human   102 NIRNKEFNY--------------LHNRNGSELDLLGMRDLLENLGYSVVIKENLTAQEMETALRQ 152

  Fly   327 -SACDRSLVRDSLVVFILSHGFEEAVYASNSIAMKITDIEDLLCSYDTLYY------------KP 378
             :|.......||..:..:||.....:..:     |..|.|..:...||::.            ||
Human   153 FAAHPEHQSSDSTFLVFMSHSILNGICGT-----KHWDQEPDVLHDDTIFEIFNNRNCQSLKDKP 212

  Fly   379 KLLIIQACQEK---LVHKKKPNELFRIDVTTVSPDQH-------------------IDMLRAMST 421
            |::|:|||:..   :|       .|..|....|.|.|                   .|.:...|:
Human   213 KVIIMQACRGNGAGIV-------WFTTDSGKASADTHGRLLQGNICNDAVTKAHVEKDFIAFKSS 270

  Fly   422 VNGYAALRHTQTGSWFIGSLCDAIDRRSASEHIADILTIVTNEVSKKRGSNDESMVPNVK--STF 484
            .....:.||...||.||..:.......|.|.|:.:|...|.:....   .|..:.:|.::  |..
Human   271 TPHNVSWRHETNGSVFISQIIYYFREYSWSHHLEEIFQKVQHSFET---PNILTQLPTIERLSMT 332

  Fly   485 RQHVYFP 491
            |....||
Human   333 RYFYLFP 339

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dredd	NP_477249.3	CASc	252..492	CDD:294037	56/278 (20%)
CASP12	NP_001177945.2	CARD_CASP1-like	6..88	CDD:260036	8/36 (22%)
		CASc	103..339	CDD:214521	51/264 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10454
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010