DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13369 and Adk

DIOPT Version :9

Sequence 1:	NP_569850.1	Gene:	CG13369 / 31007	FlyBaseID:	FBgn0025640	Length:	304	Species:	Drosophila melanogaster
Sequence 2:	NP_598840.1	Gene:	Adk / 11534	MGIID:	87930	Length:	361	Species:	Mus musculus

Alignment Length:	351	Identity:	81/351 - (23%)
Similarity:	133/351 - (37%)	Gaps:	64/351 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 AQTEVLVFG--------SAII--DFISYTTRLPK---AGETLHGH-------RFQIGYGGKGANQ 46
            |.:|.::||        ||::  ||:...:..|.   ..|..|..       :|::.|...|:.|
Mouse    19 ALSENVLFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELFDELVKKFKVEYHAGGSTQ 83

  Fly    47 CVAAARQ------GSRTALVAKLGADTFGSDYLRHLREERVNVNHVEQLAEETTGVAQIAVSDGG 105
            ......|      .........:|.|.||....|...:..|:.::.|| .|:.||.....::.|.
Mouse    84 NSMKVAQWLIQEPHKAATFFGCIGIDKFGEILKRKAADAHVDAHYYEQ-NEQPTGTCAACITGGN 147

  Fly   106 ENNIIIVVGAN--NRLSSCDVSSAKALFQEAKV-------LVCQLETPVEATLTALRAFRGVSIV 161
            .:.:..:..||  .:....|:.....|.::|:|       |....|:.::....|....|..::.
Mouse   148 RSLVANLAAANCYKKEKHLDLERNWVLVEKARVYYIAGFFLTVSPESVLKVARYAAENNRVFTLN 212

  Fly   162 NAAP--------AMADTPPELLQLASIFCVNESEAALMT-----QMPDIGNIEHAEDAVGKLIAA 213
            .:||        |:.|..|    ...|...||:|||...     :..||..|.....|:.|:.:.
Mouse   213 LSAPFISQFFKEALMDVMP----YVDILFGNETEAATFAREQGFETKDIKEIAKKAQALPKVNSK 273

  Fly   214 GANTVIITLGKLGAVFGSADSKGVCQHVAAPSVP--PEKVVDTTGAGDAFIGALAHNLARHPTRK 276
            ...|||.|.|:...:..:.:..     .|.|.:.  .|:::||.||||||:|.....|.  ..:.
Mouse   274 RQRTVIFTQGRDDTIVAAENDV-----TAFPVLDQNQEEIIDTNGAGDAFVGGFLSQLV--SDKP 331

  Fly   277 LEEHIAAACAVASQSVQLPGTQSSFP 302
            |.|.|.|....||..::..|  .:||
Mouse   332 LTECIRAGHYAASVIIRRTG--CTFP 355

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13369	NP_569850.1	ribokinase	6..303	CDD:238579	79/347 (23%)
Adk	NP_598840.1	Nuclear localization signal. /evidence=ECO:0000250	7..15
Adk	NP_598840.1	ribokinase_pfkB_like	28..360	CDD:320807	77/342 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0524
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810