DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Vsp37A and vps37c

DIOPT Version :9

Sequence 1:	NP_001259101.1	Gene:	Vsp37A / 31006	FlyBaseID:	FBgn0016038	Length:	200	Species:	Drosophila melanogaster
Sequence 2:	NP_001071253.1	Gene:	vps37c / 777738	ZFINID:	ZDB-GENE-061110-126	Length:	323	Species:	Danio rerio

Alignment Length:	165	Identity:	31/165 - (18%)
Similarity:	70/165 - (42%)	Gaps:	14/165 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 LPNLCTLSLDELKQLDRDPEFFEDFIEEMSVVQYLNEELDSMMDQVEIISRENECKGIHLVELKR 100
            :..|..||..||:.|..:.|..|....|...:|.:..|.:..:.....::.:|       :::|.
Zfish     1 MEKLQDLSQSELQDLLDNLERVESMALESDEIQNIQLEREMALAANRSLAEQN-------LDMKP 58

  Fly   101 RLSDDFTALKNLGEKCDRLNKKYFKK-------SDEYAPQHIRELLQIAASNADGDCDRHVEHFL 158
            |:.:|...|.....:.:.:.:||.:.       ..:.:|:.:...||...::.:.:.:...:.||
Zfish    59 RIENDRARLVEKYTELEAVREKYKQHCVLRDSIMGQVSPEGLLSRLQAEGASTEAESEALADEFL 123

  Fly   159 NGKTDVQTFLNTYQWSKKISTERKAKEERLGTQLS 193
            .|...:.:||..:...:.::..|:.:.|:|...||
Zfish   124 EGSISLDSFLERFLSLRSLAHTRRVRIEKLQEILS 158

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vsp37A	NP_001259101.1	Mod_r	42..181	CDD:284587	25/145 (17%)
vps37c	NP_001071253.1	Mod_r	5..146	CDD:284587	25/147 (17%)
		CENP-H	9..93	CDD:283493	15/90 (17%)
		MFMR	210..298	CDD:285072
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3270
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810