DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Vsp37A and VPS37C

DIOPT Version :9

Sequence 1:	NP_001259101.1	Gene:	Vsp37A / 31006	FlyBaseID:	FBgn0016038	Length:	200	Species:	Drosophila melanogaster
Sequence 2:	NP_060436.4	Gene:	VPS37C / 55048	HGNCID:	26097	Length:	355	Species:	Homo sapiens

Alignment Length:	148	Identity:	41/148 - (27%)
Similarity:	70/148 - (47%)	Gaps:	4/148 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 SLDELKQLDRDPEFFEDFIEEMSVVQYLNEELD-SMMDQVEIISRENECKGIHLVELKR-RLSDD 105
            :|.||::|..|.|..:....|...||.|..|.: ::.....:..|..|.:|  .:|:.| .|||.
Human     8 TLQELEELQNDSEAIDQLALESPEVQDLQLEREMALATNRSLAERNLEFQG--PLEISRSNLSDR 70

  Fly   106 FTALKNLGEKCDRLNKKYFKKSDEYAPQHIRELLQIAASNADGDCDRHVEHFLNGKTDVQTFLNT 170
            :..|:.|.|:|.....|..|.|....|..:.:|||:.....:.:.:...|.||.|:..::|||..
Human    71 YQELRKLVERCQEQKAKLEKFSSALQPGTLLDLLQVEGMKIEEESEAMAEKFLEGEVPLETFLEN 135

  Fly   171 YQWSKKISTERKAKEERL 188
            :...:.:|..|:.:.|:|
Human   136 FSSMRMLSHLRRVRVEKL 153

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vsp37A	NP_001259101.1	Mod_r	42..181	CDD:284587	38/139 (27%)
VPS37C	NP_060436.4	Mod_r	5..146	CDD:284587	38/139 (27%)
VPS37C	NP_060436.4	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	159..355
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3270
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	3	2.770