Protein Alignment CG13366 and SMTNL2

DIOPT Version :9

• Sequence 1: NP_001036254.1
• Gene: CG13366 / 31004
• FlyBaseID: FBgn0025633
• Length: 1094
• Species: Drosophila melanogaster
• Sequence 2: NP_001108446.1
• Gene: SMTNL2 / 342527
• HGNCID: 24764
• Length: 461
• Species: Homo sapiens
• Alignment Length: 575
• Identity: 136/575 - (23%)
• Similarity: 212/575 - (36%)
• Gaps: 156/575 - (27%)

  Fly   549 EAQFSQAMEEISQRAIEISRLSTLLENARSKIEELEADLSRGDKTDLSEVLDVARKEKDALEERV 613
            :||.::.:.|      .:.|....||.|...:.|....|.||.:..::|.:.:|    ..|...|
Human     6 DAQEARTVRE------ALGRYEAALEGAVRALHEDMRGLQRGVERRVAEAMRLA----GPLARTV 60

  Fly   614 AELQDQCSRSQAELRRLRDQLS--GLTEECKVVK---------------------NNAKCAVSHL 655
            |:||....|.||:|.||..|:.  ||......|.                     .:|:.| ||.
Human    61 ADLQRDNQRLQAQLERLTRQVEALGLASGMSPVPGTPGTPSPPPAPGVPDRAPRLGSARFA-SHA 124

  Fly   656 EYRLEQLQRDKDKIAGEWQALEERVAELQVQCKCHQEDKAQLQSLLAETQRH----LGDVQLKLG 716
            .:.|          :|..|:|:...|.       ..|.:....|.:.|....    .||     |
Human   125 TFSL----------SGRGQSLDHDEAS-------ESEMRKTSNSCIMENGHQPGAGPGD-----G 167

  Fly   717 EAECRLDQETQLRRKEAEEWQQFQADLLMTVRVANDFKTEALSAREQLVLDNKTQKEKIRLLEQQ 781
            ..|                             :|.:|..........:.|       .:||..|.
Human   168 PPE-----------------------------IAQNFSAPDPPRPRPVSL-------SLRLPHQP 196

  Fly   782 LEKLTKQQMQQS-ETPQSVLSTVQREMEMATRRSKLSFSRQDSRLSVKTLIESIENNKAQGKADE 845
            :..:|:...:.| ||..:.||    .|..||..   ..:...|.:.........|.|.:...:..
Human   197 VTAITRVSDRFSGETSAAALS----PMSAATLG---GLNPSPSEVITPWTPSPSEKNSSFTWSVP 254

  Fly   846 SESHYSSTSSLNSGTPDLGTTPIIFPPSSDWHESIRLPVLQSTNLHVNVGNEVGAGQGTNTSSGS 910
            |..:.:.|:|.:|.:|     |::.||.|.  .|.:.|.:  |.:|         .||.....
Human   255 SSGYGAVTASKHSNSP-----PLVTPPQSP--VSPQPPAI--TQVH---------RQGERRRE-- 299

  Fly   911 GGDLASTTKATLPLRDQQQL--AITSTQSQVQNVSQPSTPATPSSAGSSSSGGLPFGNVSKSFIS 973
                 .....|||...:.|.  |:.....|.....:....|......|.|     ||..|.|.|
Human   300 -----LVRSQTLPRTSEAQARKALFEKWEQETAAGKGKGEARARLKRSQS-----FGVASASSI- 353

  Fly   974 GERKDPLNMLAKNGGSKRNALLKWCQNKTVGYRNIDITNFSSSWNDGLAFCAILHSYLPDRIPYD 1038
                             :..||:||::||:||:::|:.||||||:||:||||::||:.||...|:
Human   354 -----------------KQILLEWCRSKTLGYQHVDLQNFSSSWSDGMAFCALVHSFFPDAFDYN 401

  Fly  1039 QLTPANKRRNFSLAFAAAESV-GIGTTLNINDMCQIER-PDWMQVMSYVTAVYKY 1091
            .|:|..:::||.|||..||:: .....:.:.||..:.| ||.|.|.:||.::|.:
Human   402 SLSPTQRQKNFELAFTMAENLANCERLIEVEDMMVMGRKPDPMCVFTYVQSLYNH 456

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13366	NP_001036254.1	Ead_Ea22	554..684	CDD:290646	35/152 (23%)
		CH	992..1092	CDD:237981	45/102 (44%)
SMTNL2	NP_001108446.1	SlyX	<56..92	CDD:294687	14/35 (40%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	87..193		21/164 (13%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	227..248		3/20 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	260..307		15/71 (21%)
		CH	354..458	CDD:237981	45/103 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG4678
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	4	3.770