DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13366 and Smtnl1

DIOPT Version :9

Sequence 1:	NP_001036254.1	Gene:	CG13366 / 31004	FlyBaseID:	FBgn0025633	Length:	1094	Species:	Drosophila melanogaster
Sequence 2:	NP_001178668.1	Gene:	Smtnl1 / 311167	RGDID:	1311701	Length:	470	Species:	Rattus norvegicus

Alignment Length:	535	Identity:	129/535 - (24%)
Similarity:	213/535 - (39%)	Gaps:	102/535 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   580 IEELEADLSRGDKTDLSEVLDVARKEKDALEERVAE-LQDQCSRSQAELRRLRDQLSGLTEECKV 643
            :|:.|.:.|....|......::|........|.||| ..::.:..........:...|....||.
  Rat     1 MEQTEGNPSEDGTTVSPTAGNLATPGSQGTAEEVAEGTAEEVAEGTVGTNDKEEPPDGAEHLCKA 65

  Fly   644 VKNNAKCAVSHLEYR-LEQLQRDKDKIAGEWQALEERVAELQVQCKCHQEDKAQLQSLLAETQRH 707
            ...........:|.. ||:|:.|..   ||.:..||..|:|       .|:|...:.....:|..
  Rat    66 ASEGGISGGCQVEASILEELKTDSQ---GEARGKEEAKADL-------AEEKGGKEDTTVSSQED 120

  Fly   708 LGDVQLKLGEAECRLDQETQLRRKEAEEWQQFQADLLMTVRVANDFKTEALSAREQLVLDNKTQK 772
            .|.            .:||   :.|..|..:.:..:|...:...|.|...|.::|:..:::|.:.
  Rat   121 TGK------------KEET---KPEPSEVTEKEEAVLPLEKQKVDEKETNLESKEKSDVNDKAEP 170

  Fly   773 E-------KIRLLEQQLEKLTKQQMQQSETPQSVLSTVQREMEMATRRSKLSFSRQDSRLSVKTL 830
            |       ::.:.|.:.|...|..::....||  |..|               ..:::|...|.|
  Rat   171 ESKEDAGAEVTVKEAETESQKKADVKDQAEPQ--LQEV---------------DGKEARSDTKEL 218

  Fly   831 IE---SIENNKAQGKADESESHYSSTSSLNSGTPDLGTTPIIFPPS-SDWHESIRLPVLQSTNLH 891
            :|   ..|..:.|||.:|||...:                 :.|.| .||.||   |..:.|:|.
  Rat   219 VEPGSPTEEQEEQGKENESEERAA-----------------VIPSSPEDWPES---PTDEGTSLS 263

  Fly   892 VN-VGNEVGAGQGTNTSSGSGGDLASTTKATLPLRDQQQLAITSTQSQVQNVSQPSTPATPSSA- 954
            .: :|.|..|...|:.|:............|.||..:::    ..::..:.||.|:.|..|.:.
  Rat   264 PDGLGPESTASGETSASASESSPSEVPESPTEPLPSEKK----KERAPERRVSAPTRPRGPRAQN 324

  Fly   955 --------GSSSSGGLPFGNVSKSFISGERKDPLNMLAKNGGSKRNALLKWCQNKTVGYRNIDIT 1011
                    |.::||  |......:..:|         |..||.| |.||:||:..|..|.::||.
  Rat   325 RKAIMDKFGGAASG--PTALFRNTKAAG---------AAIGGVK-NMLLEWCRAMTRNYEHVDIQ 377

  Fly  1012 NFSSSWNDGLAFCAILHSYLPDRIPYDQLTPANKRRNFSLAFAAAESVG-IGTTLNINDMCQIER 1075
            ||||||:.|:||||::|.:.||...|.:|.|..:|.||:|||:.||.:. ....|.::||.::..
  Rat   378 NFSSSWSSGMAFCALIHKFFPDAFDYAELDPTKRRHNFTLAFSTAEKLADCAQLLEVDDMVRLAV 442

  Fly  1076 PDWMQVMSYVTAVYK 1090
            ||...|.:|:..:|:
  Rat   443 PDSKCVYTYIQELYR 457

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13366	NP_001036254.1	Ead_Ea22	554..684	CDD:290646	22/105 (21%)
CG13366	NP_001036254.1	CH	992..1092	CDD:237981	42/100 (42%)
Smtnl1	NP_001178668.1	CH	357..457	CDD:237981	42/100 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG4678
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	4	3.770