Protein Alignment CG13366 and Smtn

DIOPT Version :9

• Sequence 1: NP_001036254.1
• Gene: CG13366 / 31004
• FlyBaseID: FBgn0025633
• Length: 1094
• Species: Drosophila melanogaster
• Sequence 2: XP_006514787.1
• Gene: Smtn / 29856
• MGIID: 1354727
• Length: 954
• Species: Mus musculus
• Alignment Length: 1141
• Identity: 228/1141 - (19%)
• Similarity: 394/1141 - (34%)
• Gaps: 318/1141 - (27%)

  Fly    25 KQQQNSSNNNRQKSQSSTSLNTAHEQQQQHSITAATTKFYAHQETASYERGVDVGDEGALLLTNQ 89
            :::..:|...|.:.|.:.. |..|.||::....||..:.....|:.:     ||.:...||.:..
Mouse    45 EEEALASKRFRAERQDNKE-NWLHSQQREAEQQAALARLAGRLESMN-----DVEELTTLLRSAG 103

  Fly    90 QQEQRRQQQQLLQQPQSNTLPQKKSKLKGQKQPKLLPVQQPHSNA-------------PEPHDPQ 141
            :.|:|:..:..:::.::..:  |.:.|.|:...: ||...|..::             |||...:
Mouse   104 EYEERKLIRAAIRRVRAQEI--KAATLAGRLCSR-LPSSGPREDSRRQAAHTLDPGKVPEPEQQE 165

  Fly   142 QPLMTSLAAVPQASATGSSSNSNINNNNALAALQDGGAAAAAAADFYQQLAAAATATATATSANG 206
            |.     ..|.:.:.|...::.::.....|.....||..::.|:.  .....:|:.......|..
Mouse   166 QQ-----TEVLEPTPTPEDTSQDVTTVTLLLRAPPGGRPSSPASP--HNSPTSASPEPLLEPAGA 223

  Fly   207 SNTSADSPVSSFP------AAAAAVAVAAVAASSYQQQQQQQQLLNNEQQQQQLLE-----ANNK 260
            ...:.::||||.|      |.:....::.|.:||  :.:...:.|....:....|:     :|.|
Mouse   224 QCPAVEAPVSSEPLPHPSEAPSPEPPMSPVPSSS--RGRVISKPLPGPTEPSDTLDSIRGFSNTK 286

  Fly   261 MQELHKQMERFRSEQMQLETRITELLPYQSEVAKLKGDLVKMQSLQEKSQM-EIGNLKYENESLR 324
            ..:        .||....:..::.|.|.|....:      :..||...||. .:|:
Mouse   287 RAD--------PSETKSCQRSLSVLSPRQPTPNR------EPTSLAGPSQFRRVGS--------- 328

  Fly   325 NRLRDVVNSPLSDAEKHQIIQDS-QRLHSSAPASIALPSTHDAHDGTPCL---TPDWDKQSSSSE 385
              :||.|....||:.....:||. .|...::|....||.        |.|   ||.....|:||.
Mouse   329 --VRDRVQKFTSDSPVVARLQDGPPRTALASPTPTRLPG--------PSLISTTPASSSSSNSSS 383

  Fly   386 ISVACLQDKIIQMEETHYSTNEELQATLQE---------LADLQTQLTDTQTENERLAEEKDVLF 441
            .|.:.......|.|..|  :..|||:..||         |..|:.:....:..:|..:....|..
Mouse   384 PSPSDTSSHKKQRELAH--SLAELQSCPQEEGPGGRGLALRSLENRAGGPKPCSEEPSTPPPVAV 446

  Fly   442 -------QSLCRQTEKLNESRTQISTLQELLLRDTKQPAPEVSASEREQKLLDLIKTSQEEREAV 499
                   ......|.::.:.|.|.||.:.||  .|.....|::...|...  .|:.||...:..:
Mouse   447 GTGEPGGSMKTTFTIEIKDGRGQASTGRVLL--PTGNQRAELTLGLRAPP--TLLSTSSGGKNTI 507

  Fly   500 LLKQE-----ELGAEL---------------AEMKQAREAGQLELQRQRERIALLDSQLDAANAE 544
            .....     .||:..               ...|.|.:||.....             ..|.:.
Mouse   508 THISNPGTVTRLGSVTHVTTFSHASPGNRGGCNFKAAEDAGTPVAH-------------PPAFST 559

  Fly   545 RRQ---GEAQFSQAMEEISQRAIEISRLSTLLENARSKIEELEADLSRGDKTDLSEVLDVARKEK 606
            ||.   |.::.|..||......     .||.:| |.:..|:...|.....::.||      .:|.
Mouse   560 RRSSSGGPSRRSSLMEPDPAEP-----PSTTVE-AANGAEQARVDKGPEGRSPLS------AEEL 612

  Fly   607 DALEERVAELQDQCSRSQAELRRLRDQLSGLTEECKVVKNNAKCAVSHLEYRLEQLQRDKDKIAG 671
            .|:|:            :..|.::.||.:.. ||.|:::...:        .|.|.:||
Mouse   613 TAIED------------EGVLDKMLDQTTNF-EERKLIRAALR--------ELRQRKRD------ 650

  Fly   672 EWQALEERVAELQVQCKCHQEDKAQLQSLLAETQRHLGDVQLKLGEAECRLDQETQLRRKEAEEW 736
                               |.||        |.:|.|.:.:.:.||:...:..||..|..:
Mouse   651 -------------------QRDK--------ERERRLREARARPGESRSNVATETTTRHSQ---- 684

  Fly   737 QQFQADLLMTVRVANDFKTEALSAREQLVLDNK-TQKEKIRLLEQQLEKLTKQQMQQSETPQSVL 800
                       |.|:......::..|:||..|. ||..:...:|....:..:.....|.|..:.:
Mouse   685 -----------RAADGSTVGTVTKTERLVHSNDGTQTARTTTVESSFMRRLENGSSSSSTTTTTV 738

  Fly   801 STVQREMEMATRRSKLS---FSRQDSRLSVKTLIESIENNKAQGKADESESHYSSTSSLNSGTPD 862
            .|.......::..||..   |.|:|...|....:.::|..:|:.|
Mouse   739 QTKSFSSSSSSSSSKKMGSIFDREDQTSSRPGSLAALERRQAEKK-------------------- 783

  Fly   863 LGTTPIIFPPSSDWHESIRLPVLQSTNLHVNVGNEVGAGQGTNTSSGSGGDLASTTKATLPLRDQ 927
                                             .|:...|....:|.|                |
Mouse   784 ---------------------------------KELMKAQSLPKTSAS----------------Q 799

  Fly   928 QQLAITSTQSQVQNVSQPSTPATPSSAGSSSSGGLPFGNVSKSFISGERKDPLNMLAKNGGSKRN 992
            .:.|:.....:..:...|.||.|  :...|:|.|:|                      |..|.:.
Mouse   800 ARKAMIEKLEKEGSAGGPGTPRT--AVQRSTSFGVP----------------------NANSIKQ 840

  Fly   993 ALLKWCQNKTVGYRNIDITNFSSSWNDGLAFCAILHSYLPDRIPYDQLTPANKRRNFSLAFAAAE 1057
            .||.||:.||.||.::||.||||||:||:||||::|::.|:...|.||:|.|:|:||.:||::||
Mouse   841 MLLDWCRAKTRGYEHVDIQNFSSSWSDGMAFCALVHNFFPEAFDYGQLSPQNRRQNFEMAFSSAE 905

  Fly  1058 S-VGIGTTLNINDMCQI-ERPDWMQVMSYVTAVYKY 1091
            . |.....:.:.||..: ::||...|.:||.::|.:
Mouse   906 MLVDCVPLVEVEDMMIMGKKPDPKCVFTYVQSLYNH 941

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13366	NP_001036254.1	Ead_Ea22	554..684	CDD:290646	23/129 (18%)
		CH	992..1092	CDD:237981	45/102 (44%)
Smtn	XP_006514787.1	Smoothelin	1..34	CDD:372157
		Smoothelin	73..122	CDD:372157	9/53 (17%)
		PHA03247	<107..454	CDD:223021	73/393 (19%)
		Smoothelin	601..648	CDD:372157	13/73 (18%)
		CH	839..943	CDD:237981	45/103 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG4678
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	4	3.770