Protein Alignment spdi and Smtnl2

DIOPT Version :10

• Sequence 1: NP_001036254.1
• Gene: spdi / 31004
• FlyBaseID: FBgn0025633
• Length: 1094
• Species: Drosophila melanogaster
• Sequence 2: NP_808444.1
• Gene: Smtnl2 / 276829
• MGIID: 2442764
• Length: 456
• Species: Mus musculus
• Alignment Length: 574
• Identity: 133/574 - (23%)
• Similarity: 203/574 - (35%)
• Gaps: 187/574 - (32%)

  Fly   566 ISRLSTLLENARSKIEELEADLSRGDKTDLSEVLDVARKEKDALEERVAELQDQCSRSQAELRRL 630
            :.|....||.|...:.|....|.||.:..::|.|.:|    ..|...|||||....|.||:|.||
Mouse    17 LGRYEAALEGAVRALHEDMQGLQRGVERRVAEALRLA----GPLARTVAELQRDNQRLQAQLERL 77

  Fly   631 RDQLSGL-------------------TEECKVVKNNAKCAVSHLEYRLEQLQRDKDKIAGEWQAL 676
            ..|:..|                   |...:..:.......||..:.|          :|...::
Mouse    78 TRQVEALGLATGVSPAPGTPSPPPAATVTDRAPRLGTARFSSHATFSL----------SGRSPSV 132

  Fly   677 EERVAELQVQCKCHQEDKAQLQSLLAETQRHLGDVQLKLGEAECRLDQETQLRRKEAEEWQQFQA 741
            |            |.|               ..|::::.....|.|:...||....|....:.|.
Mouse   133 E------------HDE---------------ASDLEVRRASNSCILENGHQLDAGPANGSSEVQT 170

  Fly   742 DLLMTVRVANDFKTEALSAREQLVLDNKTQKEKIRLLEQQLEKLTKQQMQQSETPQSVLSTVQRE 806
                                                          ...|:...|:.|..:::..
Mouse   171 ----------------------------------------------SSAQEPPRPRPVSLSLRMP 189

  Fly   807 MEMATRRSKLSFSRQDSRLSVKTLIESIENNKAQGKADESESHYSSTSSLNSGTPDLGTTPIIFP 871
            .:..|..:::|                   .|..|  :.|.|..|.||:...|    |.||....
Mouse   190 HQPVTAVTRVS-------------------EKFSG--ETSASALSPTSAAIVG----GFTPSPSE 229

  Fly   872 PSSDWHESIRLPVLQSTNLHVNVGNEVGAGQGTNTSSGSGGDLASTTKATLPLRDQQQLAITSTQ 936
            ..|.|..|   |..:|::.             |.:.||||....:..|.    :|...| :|..|
Mouse   230 AISPWTPS---PTEKSSSF-------------TRSLSGSGYGAVTAGKR----KDSPPL-VTPPQ 273

  Fly   937 SQVQNVSQPSTPA-------------------TPSSAGSSSSGGL----PFGNVSKSFISGERKD 978
            |...  |||  ||                   .|.::|:.:...|    .....||.  .||.:.
Mouse   274 SPPS--SQP--PAMTQAPRQGERRRELVRSQTLPRTSGAQARKALFEKWEQDTASKG--KGETRA 332

  Fly   979 PLNMLAKNG----GSKRNALLKWCQNKTVGYRNIDITNFSSSWNDGLAFCAILHSYLPDRIPYDQ 1039
            .|......|    .|.:..||:||::|||||:::|:.||||||:||:||||::||:.||...|:.
Mouse   333 KLKRSQSFGVASASSIKQILLEWCRSKTVGYQHVDLQNFSSSWSDGMAFCALVHSFFPDAFDYNA 397

  Fly  1040 LTPANKRRNFSLAFAAAESV-GIGTTLNINDMCQIER-PDWMQVMSYVTAVYKY 1091
            |:|..:::||.|||..||:: .....:.:.||..:.| ||.|.|.:||.::|.:
Mouse   398 LSPTQRQKNFELAFTMAENLANCERLIEVEDMMVMGRKPDPMCVFTYVQSLYNH 451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spdi	NP_001036254.1	SMC_prok_B	<257..>845	CDD:274008	47/297 (16%)
		Smc	<501..>794	CDD:440809	41/246 (17%)
		CH_CYTS	982..1093	CDD:409048	48/116 (41%)
Smtnl2	NP_808444.1	PRK09039	<8..>84	CDD:181619	24/70 (34%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	120..140		6/56 (11%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	154..190		7/81 (9%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	220..310		27/118 (23%)
		CH_SMTNL2	347..453	CDD:409110	47/105 (45%)