Protein Alignment CG13366 and specc1

DIOPT Version :9

• Sequence 1: NP_001036254.1
• Gene: CG13366 / 31004
• FlyBaseID: FBgn0025633
• Length: 1094
• Species: Drosophila melanogaster
• Sequence 2: XP_017946933.1
• Gene: specc1 / 100380013
• XenbaseID: XB-GENE-956924
• Length: 1057
• Species: Xenopus tropicalis
• Alignment Length: 1119
• Identity: 316/1119 - (28%)
• Similarity: 502/1119 - (44%)
• Gaps: 259/1119 - (23%)

  Fly   150 AVPQAS---ATGSSSNS-----------NINNNNALAALQDGGAAAAAAADFYQQLAAAATA--- 197
            |:|..:   .|..|:||           ..::::.|.  :.||::.:..:...:.:...|.:
 Frog    24 AIPTIAFGMKTSRSTNSLAFESRLSKLKRASSDDMLT--KPGGSSTSTTSRMKKTITTGAISELT 86

  Fly   198 -----TATATSANGSNTSADSPVS-SFPAAAAAVAV-AAVAASSYQQQQQQQQLLNNEQQQQQLL 255
                 :||.|||....|...:|.. |.|.:...||: :.|.|::       ::.|.:........
 Frog    87 ESKYRSATGTSAAARRTGIPAPRELSTPVSRDRVALRSPVNANA-------KKTLPSPSSPSTPT 144

  Fly   256 EANNKMQELHKQMERFRSEQMQLETRITELL----PYQSEVAKLKGDLVK--------------- 301
            .:.|.......:.|..:..:..||.::.|||    ...||:.||:.:|.|
 Frog   145 PSKNVRTPTRPKQENEQINKTVLEIQVKELLAEAKTKDSEICKLRSELQKCKDKESPSPEVLNSI 209

  Fly   302 --------------------MQSLQEK---SQMEIGNLKYENESLRNRLRDVVNSPLSD------ 337
                                :::||||   |.:|:..|:.||..|:.:|..:..|||||
 Frog   210 GPLAELHDINNVALSDPEALIRTLQEKNTNSLLELAILRKENADLKQKLHALEQSPLSDTITSNG 274

  Fly   338 AEKHQIIQDSQR---------------------------LHSSAPAS-----------------I 358
            .:...::..|.:                           ||.|..:|                 |
 Frog   275 TDSSSLLSPSTQGTNIGCQLKSPPAGETGDCRIPGSESGLHISGSSSSDVTKASISPDASDFEHI 339

  Fly   359 A-LPSTHDAHDGTPCLTPDWDKQSSS----SEISVACLQDKIIQMEETHYSTNEELQATLQELAD 418
            | :||...:....||.........||    |::|||.|.::|.:|||.|:||.||||||||||:|
 Frog   340 ADMPSRPTSTGSIPCQGSKCSTSGSSPNNISDLSVASLTERIHKMEENHHSTAEELQATLQELSD 404

  Fly   419 LQTQLTDTQTENERLAEEKDVLFQSLCRQTEKLNESRTQISTLQELLLRDTKQPAPEV--SASER 481
            ....:.:...|:|:|.|||..|..:|.:|.::..:...:...|..||....|....|:  ..:|.
 Frog   405 QNLMVQELTMESEKLVEEKAFLETNLQQQRQRAEQLSQENERLMGLLKDRAKTEEAEIHGKLTET 469

  Fly   482 EQKLLDLIKTSQEEREAVLLKQEELGAELAEMKQAREAGQLELQRQRERIALLDSQLDAANAERR 546
            |:|.|:|::.||.|||.:|..|::|.:.|..:::..:..|...::..|.:..|...||....|:.
 Frog   470 EKKYLELVEKSQFEREKLLNIQQQLTSSLRSLEKEHQEAQAMRKKLEEEVDKLQRLLDTQRKEKN 534

  Fly   547 QGEAQFSQAMEE--ISQRAIEISR--LSTLLENARSKIEELEADLSRGD---KTDLSEVLDVARK 604
                ..::|:|:  ::...::|..  |...||..|.|..|:.| :.:|.   .|::.|:|..|..
 Frog   535 ----VTAKALEDQKVTNEGLKIENNCLKAQLEGERQKAAEITA-VGKGSGSGNTEIQEMLKSAHA 594

  Fly   605 EKDALEERVAELQDQCSRSQAELRRLRDQLSGLTEECKVVKNNAKCAVSHLE---YRLEQLQRDK 666
            ||:.||...:||:.:..|:.:|:::|:..|:.:..||..:|.........|:   .:|::...:|
 Frog   595 EKEHLELTCSELRQELLRANSEVKQLQCLLAKVETECHDLKELGDLREEQLKSANLKLQERSSEK 659

  Fly   667 DKIAGEWQALEERVAELQVQCKCHQEDKAQLQSLLAETQRHLGDVQLKLGEAECRLDQETQLR-- 729
            |.   |.:.::|.:.||:.|.:.|:..|.....|:::.:..:..::      |.:.|.|.||:
 Frog   660 DT---EIKDMKETIFELEDQVEQHRAVKLHNNQLISDLENKVDKLE------EQKQDLERQLKLL 715

  Fly   730 ----RKEAEEWQQFQADLLMTVRVANDFKTEALSAREQLVLDNKTQKEKIRLLEQQLEKLTKQQM 790
                :::||||::|||||...|.||||.|.|:                      ||..:..|:::
 Frog   716 NKQMKEDAEEWRRFQADLQTAVVVANDIKCES----------------------QQELRAVKRRL 758

  Fly   791 QQSETPQSVLSTVQREMEMATRRSKLSFSRQDSRLSVKTLIESI-ENNKAQGKADESESHYSSTS 854
            |:.|...:.|   .||:|      :|..|||.|     ..:||: |:|:.:.   .|.:|..:.:
 Frog   759 QEEEERSACL---HRELE------ELQGSRQPS-----GEVESVDEDNRIRW---PSVAHTQAPT 806

  Fly   855 SLNSGTPDLGTTPIIFPPSSDWHESIRLP-VLQSTNLHVNVGNEVGAGQGTNTSSGSGGDLASTT 918
            |                       |..|| .::|.....::||:.|.||.....|.....|:...
 Frog   807 S-----------------------SSELPATVKSLIKSFDLGNQGGVGQNIPVHSVPRSPLSGIP 848

  Fly   919 KATLP---LRDQQQLAITS--------TQSQVQNVSQ------PSTP-----ATPSSAGSSSSGG 961
            ..|.|   :...|:|:::|        .:.|:.|..:      ..||     .:||....::...
 Frog   849 VRTAPAAAVSPIQRLSVSSNAKLSGKEAERQLDNADKLKGQRDDFTPDRFPRKSPSLESLNTHTA 913

  Fly   962 LPFGNVSK----------SFISGERKDPLNMLAKN-GGSKRNALLKWCQNKTVGYRNIDITNFSS 1015
            |.||:.:.          |.||.||||||..||:. |||||||||||||.||.||.|||||||||
 Frog   914 LGFGSRTSPIALDSLSHHSKISVERKDPLAALAREYGGSKRNALLKWCQKKTEGYSNIDITNFSS 978

  Fly  1016 SWNDGLAFCAILHSYLPDRIPYDQLTPANKRRNFSLAFAAAESVGIGTTLNINDMCQIERPDWMQ 1080
            ||:|||||||:||:|||..|||.:|...:|:||..|||.|||||||.|:|.:|:|...:||||..
 Frog   979 SWSDGLAFCALLHTYLPAHIPYQELNSQDKKRNLMLAFQAAESVGIKTSLELNEMMFTDRPDWQC 1043

  Fly  1081 VMSYVTAVYKYFET 1094
            ||.||..:||||||
 Frog  1044 VMHYVAQIYKYFET 1057

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13366	NP_001036254.1	Ead_Ea22	554..684	CDD:290646	35/139 (25%)
		CH	992..1092	CDD:237981	66/99 (67%)
specc1	XP_017946933.1	DUF641	<157..195	CDD:368160	11/37 (30%)
		DUF4670	<380..544	CDD:374040	54/167 (32%)
		SMC_prok_B	468..>780	CDD:274008	92/356 (26%)
		CH	954..1057	CDD:366016	69/102 (68%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	222	1.000	Domainoid score	I2533
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	386	1.000	Inparanoid score	I1976
OMA	1	1.010	-	-		QHG45969
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002287
OrthoInspector	1	1.000	-	-		otm49206
Panther	1	1.100	-	-	LDO	PTHR23167
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1969
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	9.070