Protein Alignment spdi and smtn

DIOPT Version :10

• Sequence 1: NP_001036254.1
• Gene: spdi / 31004
• FlyBaseID: FBgn0025633
• Length: 1094
• Species: Drosophila melanogaster
• Sequence 2: XP_017946876.2
• Gene: smtn / 100216161
• XenbaseID: XB-GENE-951898
• Length: 1051
• Species: Xenopus tropicalis
• Alignment Length: 1070
• Identity: 233/1070 - (21%)
• Similarity: 396/1070 - (37%)
• Gaps: 301/1070 - (28%)

  Fly   233 SSYQQQQQQQQLLNNEQQQQQLLEA-------NNKMQELHKQMERFR--SEQMQLETRITELLPY 288
            |..|:.::.|...:.|:|||:.|.|       .|.::||...:...:  .|:..:...|.::...
 Frog    59 SHEQENKENQPRADREEQQQRALNALTIRLQNINDLEELTSLLRNSKEYEERKLIRAAIRKVRND 123

  Fly   289 QSEVAKLKGDLVKMQSLQE------KSQMEIGN----LKYENESLRNR---------LRDVVN-- 332
            :.|.|.|.|.|::..|.::      |||..:||    |..|.|.|..|         ||...|
 Frog   124 EIEAASLGGMLIRQSSERDNGKLVCKSQDAVGNLVPSLAQEREDLEERQKIRAQIHELRSAQNGG 188

  Fly   333 SPLSDAEKHQIIQDSQRLHSSAPASIALPSTHDAHDGTPCLTPDWDKQSSSSEISVACLQDKIIQ 397
            |.::.:::   |:.:..|....|....|||:..:...|...|....:.||||......|.....:
 Frog   189 SHIAGSKE---IESNMLLRLKVPTKEQLPSSTSSSSSTSSFTSFSSEPSSSSHCQATELLSLSAE 250

  Fly   398 ME-ETHYSTNEELQATLQELADLQTQLTDTQTENERLAEEKDVLFQSLCRQTEKLNESRTQI--- 458
            .| :.|.:.||.......|.:..:|:    :..|..:|..|         |..|..:....:
 Frog   251 FEGQPHNNRNEVFMEPSAEDSGTETR----EQPNTHVASHK---------QNVKSEQKPLPVWTG 302

  Fly   459 ---STLQELLLRDTKQPAPE----VSASE-----------REQKLLDLIKTSQEEREAVL----- 500
               |.:...|..|.|:..||    .|.||           |...:.|.:|...||..:|.
 Frog   303 RADSHIISRLGADNKESFPEGVTSASCSEPDDQTSMPPFRRAYSVRDRVKKFSEESSSVTTPALG 367

  Fly   501 -----LKQEEL---GAELAEMKQAREAGQLELQRQRERIALLDSQ-------------------- 537
                 ::.|..   ||.:.:.......||...|:..:....:..|
 Frog   368 FRFGSMRAERAPVRGAHVLQQHSLLSVGQENNQKAAQNARFVTKQEVTRTVSGPCTRRLDGIPTA 432

  Fly   538 ------------------LDAANAERRQGEAQFSQ-----AMEEISQRAIEISRLSTLLE--NAR 577
                              |:.:.:...:|.:..|.     :..|:: |.:..|:.|.:|:  :.|
 Frog   433 GTQSTNKIQSFKSPFIPELNNSRSTSLKGSSSLSSTGPCTSSREVN-RGLPQSQGSFILKQNSGR 496

  Fly   578 SKIEELEADLSRGDKTDLSEVLDVARKE---------------KDALEER---------VAELQD 618
            |:..:|:..|...::..:.|..|.|..|               |...||.         ..|::|
 Frog   497 SQENQLKVPLPMTERGRIDENSDGANTEGPGSLQSSTHLCKSTKGTREETEDTDMKTLLTIEIKD 561

  Fly   619 ------------QCSRSQAEL----------------------------RRLRDQL-----SGLT 638
                        |....:|||                            |.:|.:.     ||:|
 Frog   562 GRNQTTSSRVVGQPGNQRAELMLGLTSSPFRINSGFSTSNDGASSGITTRSIRTETRTTTQSGIT 626

  Fly   639 EECKVVKNNAKCAVSHLEYRLEQLQRDKDKIAG-EWQALEERVAEL------------QVQCKCH 690
            ....|:|...:....|   ::|:..:|:.:.:| |..|:....||.            :|:.:..
 Frog   627 SSSNVIKEKKRLRSDH---QMEERDQDRQQCSGEEGSAVSSVPAEAPLSDSTCGGDIGEVEAETP 688

  Fly   691 QEDKAQLQSLL-AETQRHLGDVQLKLGEAECRLDQETQLRRKEAEEWQQFQADLLMTVRVA-NDF 753
            ||...||:..| :.|::...:.:.||...:....:|.::..|..::...|:...|  :|.| .|.
 Frog   689 QETPQQLEVFLPSTTEKAEPENKGKLTAEDLNAIEEEEVLDKMLDKATDFEERKL--IRAAMRDL 751

  Fly   754 KTEALSAREQLVLDNKTQKEKIRLLEQQLEKLTKQQMQQSETPQ--SVLSTVQREMEMATRRSKL 816
            :......||: ..:.:.|:.|.:..|.||.:.|:..::||||..  |.:|||       |:..:|
 Frog   752 RQRKREQREK-EREQRLQELKNKERESQLARSTETSIRQSETTNHGSAVSTV-------TKTQRL 808

  Fly   817 SFSRQDSRLSVKTLIESIENNKAQGKADESESHYSSTSSLNSGTPDLGTTPIIFPPSSDWHESIR 881
            ..|...|:.|..|.:|:    ....:::..::...:.||.::.:..:|:   ||....:
 Frog   809 VQSNDGSKTSSTTTLEA----SYMKRSENGDTIVQTKSSFSATSKKVGS---IFDREDE------ 860

  Fly   882 LPVLQSTNLHVNVGNEVGAGQGTNTSSGSGGDLASTTKATLPLRDQQQLAITSTQSQVQNVSQPS 946
                                           .|:.....|...|.|.:......::|    |.|.
 Frog   861 -------------------------------GLSRANSMTAMERRQAERKKELMKAQ----SLPK 890

  Fly   947 TPATPS-----------SAGSSSSGGLPFGNVS--KSFISGERKDPLNMLAKNGGSKRNALLKWC 998
            ||||.:           |.||||..   |..|:  :|...|         ..|..|.:..||.||
 Frog   891 TPATQARKAMIEKMEKESGGSSSPA---FAKVATPRSAAFG---------VPNANSIKQMLLDWC 943

  Fly   999 QNKTVGYRNIDITNFSSSWNDGLAFCAILHSYLPDRIPYDQLTPANKRRNFSLAFAAAES-VGIG 1062
            :.||.||.:::|.||||||:||:||||::|::.|:...|:||.|.|:|:||.|||:|||. |...
 Frog   944 KAKTRGYEHVNIQNFSSSWSDGMAFCALVHNFFPEAFDYNQLNPQNRRKNFDLAFSAAEMLVDCV 1008

  Fly  1063 TTLNINDMCQI-ERPDWMQVMSYVTAVYKY 1091
            ..:.:.||..: :|||...|.:||.::|.:
 Frog  1009 PLVEVEDMMIMGKRPDSKCVFTYVQSLYNH 1038

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spdi	NP_001036254.1	SMC_prok_B	<257..>845	CDD:274008	151/783 (19%)
		Smc	<501..>794	CDD:440809	72/424 (17%)
		CH_CYTS	982..1093	CDD:409048	49/112 (44%)
smtn	XP_017946876.2	Smoothelin	<10..41	CDD:463614
		Smc	<11..>186	CDD:440809	32/126 (25%)
		Smoothelin	75..121	CDD:463614	10/45 (22%)
		Smoothelin	706..755	CDD:463614	9/50 (18%)
		CH_SMTNA	934..1044	CDD:409107	48/105 (46%)