DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment vnd and nkx2.1

DIOPT Version :9

Sequence 1:NP_476786.2 Gene:vnd / 31003 FlyBaseID:FBgn0261930 Length:723 Species:Drosophila melanogaster
Sequence 2:NP_571851.1 Gene:nkx2.1 / 81883 ZFINID:ZDB-GENE-010404-1 Length:346 Species:Danio rerio


Alignment Length:371 Identity:116/371 - (31%)
Similarity:159/371 - (42%) Gaps:97/371 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly   374 SFGDEMSSYH--HMAQTMLQ--HSGRSAWIKENELYGTQQPASPDSTSPVTSEVSYTYIGSNCQT 434
            :.|..::||.  .:.|..:|  |.|.:..:          ||:...|:...|::|:|.:|..|..
Zfish    33 NLGAPLASYRQPQVTQAAMQQHHMGHNGTV----------PAAYHMTAAGVSQLSHTAMGGYCNG 87

  Fly   435 SPALSGDYKSYSRSADSDALSVGDALHTLHGSSGNGSAGGAPTAHALHNNNNNTTNNNNHSLKAE 499
            :.....|..:|.           |.:.            |:.||.:.:.     ||.:.......
Zfish    88 NLGNMSDLPAYQ-----------DGMR------------GSTTATSWYG-----TNPDPRFSTIS 124

  Fly   500 GINGAGSGHDDSLNEDGIEEDIDDVDDADGSGGGDANGSDGLPNKKRKRRVLFTKAQTYELERRF 564
            ...|:.||    :|. |....:..:.|. |.|.|....:     .:|||||||::||.|||||||
Zfish   125 RFMGSSSG----MNM-GSMSTLSSLADV-GKGMGPLTST-----PRRKRRVLFSQAQVYELERRF 178

  Fly   565 RQQRYLSAPEREHLASLIRLTPTQVKIWFQNHRYKTKRAQNEKGYEGHPGLLHGHATHPHHPSAL 629
            :||:||||||||||||:|.||||||||||||||||.||...:|..:......:|.......    
Zfish   179 KQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQAKDKVSQQQMQQDNGSCQQQQQ---- 239

  Fly   630 PSPRRVAVPVLVRNGKPCLGDSSKLGADCVSVSSATATAMQNAAAHHLVALN------------- 681
             |||||||||||::||||.|.           |....|.:||   ||....|             
Zfish   240 -SPRRVAVPVLVKDGKPCQGS-----------SHTPNTGVQN---HHHQGGNVMFMTNTSLSMSQ 289

  Fly   682 ------GAAAY-----QHAAAAAAGLHAHAHAHAHAHGHGHPHAHA 716
                  |:|..     ||||:..: |.......:|.:..|..:..|
Zfish   290 HQSQQVGSAGQSLDLGQHAASPPS-LQTQVPGLSHLNSSGSEYGAA 334

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
vndNP_476786.2 Homeobox 548..601 CDD:278475 45/52 (87%)
nkx2.1NP_571851.1 Homeobox 162..215 CDD:278475 45/52 (87%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0842
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X524
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
32.810

Return to query results.
Submit another query.