Protein Alignment vnd and NKX3-2

DIOPT Version :10

• Sequence 1: NP_476786.2
• Gene: vnd / 31003
• FlyBaseID: FBgn0261930
• Length: 723
• Species: Drosophila melanogaster
• Sequence 2: NP_001180.1
• Gene: NKX3-2 / 579
• HGNCID: 951
• Length: 333
• Species: Homo sapiens
• Alignment Length: 256
• Identity: 85/256 - (33%)
• Similarity: 115/256 - (44%)
• Gaps: 61/256 - (23%)

  Fly   406 GTQQPASPDSTSPVTSEVSYTYIGSNCQTSPALSGDYKSYSRSADSDALSVGDALHTLHGSSGNG 470
            ||:..|...:.||           ....:..|||.:.:|..|.||:            .|:||.|
Human    76 GTRTAAGRTAESP-----------EGWDSDSALSEENESRRRCADA------------RGASGAG 117

  Fly   471 SAGGA-----PTAH-ALHNNNNNTTNNNNHSLKAEGINGAGSGHDDSLNEDGIEEDIDDVDD-AD 528
            .|||:     |... |...:........:.|..:..::|..|...:   :||:......|.. ..
Human   118 LAGGSLSLGQPVCELAASKDLEEEAAGRSDSEMSASVSGDRSPRTE---DDGVGPRGAHVSALCS 179

  Fly   529 GSGGGDANGSDGL-----------PNKKRKRRVLFTKAQTYELERRFRQQRYLSAPEREHLASLI 582
            |:|||..:|..|:           |.|||. |..|:.||.:||||||..|||||.|||..||:.:
Human   180 GAGGGGGSGPAGVAEEEEEPAAPKPRKKRS-RAAFSHAQVFELERRFNHQRYLSGPERADLAASL 243

  Fly   583 RLTPTQVKIWFQNHRYKTKRAQNEKGYEGHPGLLHGHATHPHHPSALPSPRRVAVPVLVRN 643
            :||.|||||||||.||||||.|..      ..||          ::.|:.::|||.||||:
Human   244 KLTETQVKIWFQNRRYKTKRRQMA------ADLL----------ASAPAAKKVAVKVLVRD 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vnd	NP_476786.2	Homeodomain	546..602	CDD:459649	36/55 (65%)
NKX3-2	NP_001180.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	65..113		12/59 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	138..212		17/77 (22%)
		Homeodomain	207..263	CDD:459649	37/56 (66%)