Protein Alignment vnd and BARX1

DIOPT Version :10

• Sequence 1: NP_476786.2
• Gene: vnd / 31003
• FlyBaseID: FBgn0261930
• Length: 723
• Species: Drosophila melanogaster
• Sequence 2: NP_067545.3
• Gene: BARX1 / 56033
• HGNCID: 955
• Length: 254
• Species: Homo sapiens
• Alignment Length: 295
• Identity: 71/295 - (24%)
• Similarity: 99/295 - (33%)
• Gaps: 124/295 - (42%)

  Fly   352 AAAAAAVAAGQYLPNLPKNFPGSFGDEMSSYHHMAQTMLQ----HSGRSAWIKENELYGTQQPAS 412
            |.||||.|||:.|         .||         .|.:|.    || ..|.:|..:....:.|.:
Human    45 APAAAAAAAGELL---------KFG---------VQALLAARPFHS-HLAVLKAEQAAVFKFPLA 90

  Fly   413 PDSTSPVTSEVSYTYIGSNCQTSPALSGDYKSYSRSADSDALSVGDALHTLHGSSGNGSAGGAPT 477
            |...|.::|.:        ....|.|.|                               |.|||
Human    91 PLGCSGLSSAL--------LAAGPGLPG-------------------------------AAGAP- 115

  Fly   478 AHALHNNNNNTTNNNNH---SLKAEG-INGAGSGHDDSLNEDGIEEDIDDVDDADGSGGGDANGS 538
                            |   .|:..| :..||.|      |.|.:
Human   116 ----------------HLPLELQLRGKLEAAGPG------EPGTK-------------------- 138

  Fly   539 DGLPNKKRKRRVLFTKAQTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHRYKTKRA 603
               ..|.|:.|.:||:.|...||:||.:|:|||.|:|..||..:.|:..|||.|:||.|.|.|:.
Human   139 ---AKKGRRSRTVFTELQLMGLEKRFEKQKYLSTPDRIDLAESLGLSQLQVKTWYQNRRMKWKKI 200

  Fly   604 QNEKGYEGHPGLLHGHATHPHHPSALPSPRRVAVP 638
            ..:.|     ||     ..|..|..  .|::.::|
Human   201 VLQGG-----GL-----ESPTKPKG--RPKKNSIP 223

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vnd	NP_476786.2	Homeodomain	546..602	CDD:459649	26/55 (47%)
BARX1	NP_067545.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20
		Homeodomain	143..199	CDD:459649	26/55 (47%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	204..254		7/32 (22%)