Protein Alignment vnd and E5

DIOPT Version :10

• Sequence 1: NP_476786.2
• Gene: vnd / 31003
• FlyBaseID: FBgn0261930
• Length: 723
• Species: Drosophila melanogaster
• Sequence 2: NP_524825.1
• Gene: E5 / 45396
• FlyBaseID: FBgn0008646
• Length: 524
• Species: Drosophila melanogaster
• Alignment Length: 629
• Identity: 122/629 - (19%)
• Similarity: 157/629 - (24%)
• Gaps: 315/629 - (50%)

  Fly     2 TTSASLERTPSKRDRDRER-----DNSSGLGSAGSLPASPQSAITVSP---SSPATPKRPLRTST 58
            :||.|...|.|.....:.:     |:..|..|..|.|.. .|.|:..|   .|||:|     |:|
  Fly    31 STSVSASSTVSASASSKPKLAFSIDSIVGESSTRSAPLR-VSVISSPPPRSESPASP-----TNT 89

  Fly    59 PSLERKRERE----DREDREDRKERQERHERDRDHE------RFAAVFSTASTTVPTNTSSSSGL 113
            .:..|:..|.    .|.|..||....:|....|...      ..||..:||.:..|   ||.:|.
  Fly    90 NNSGRRTPRGYIYCRRRDSLDRSRSPQRSPVSRSPSPPNAGGNPAAAGNTAKSGDP---SSGTGN 151

  Fly   114 APEQLR-IPTGAAAFSGFPGLHSMSSLMLPSSAAVAAAAAAPFLPWSPILLPPWNHALLPAAFYP 177
            .|..:| :|..|      |.|..:.:...|::.|| ..|..|..|..|   ||:    |.|.|
  Fly   152 PPTLIRPLPLPA------PNLALIGNRTSPNAMAV-RMAGPPHPPSQP---PPF----LAAQF-- 200

  Fly   178 AALRNALPGLFDAKVPSSQRSGFHISDILNLEGSELKNAAAAAAAAAHHGSDLSHHSASESTSGH 242
                                                    ..|||.|||               |
  Fly   201 ----------------------------------------QMAAALAHH---------------H 210

  Fly   243 RGQGSHTSPSALSPTPAGVSADEHHNGSGTGGGAGEADHHSTTEHHAPPSHPQQQHPHHQQHHHP 307
            : |........|.|.|.|                             ||..|   |||......|
  Fly   211 Q-QQQQQQQQQLPPVPTG-----------------------------PPHGP---HPHLPPGQIP 242

  Fly   308 HLLLPQQHHQQAVAPLPLAHHQSGEAQSHAHANAAAAH--LLASHNAAAAAAVAAGQYLPNLPKN 370
            ..:.|...|..  .|.|..||..|.| .|...::...:  ||:.|          |:..|..|.|
  Fly   243 LGIFPGGPHPG--HPPPHGHHPFGSA-PHLIRDSYPLYPWLLSRH----------GRIFPRFPGN 294

  Fly   371 FPGSFGDEMSSYHHMAQTMLQHSGRSAWIKENELYGTQQPASPDSTSPVTSEVSYTYIGSNCQTS 435
            |                 :.|
  Fly   295 F-----------------LFQ-------------------------------------------- 298

  Fly   436 PALSGDYKSYSRSADSDALSVGDALHTLHGSSGNGSAGGAPTAHALHNNNNNTTNNNNHSLKAEG 500
                                                                             
  Fly   299 ----------------------------------------------------------------- 298

  Fly   501 INGAGSGHDDSLNEDGIEEDIDDVDDADGSGGGDANGSDGLPNKKRKR-RVLFTKAQTYELERRF 564
                                                     |.:|.|| |..|:..|..:||..|
  Fly   299 -----------------------------------------PFRKPKRVRTAFSPTQLLKLEHAF 322

  Fly   565 RQQRYLSAPEREHLASLIRLTPTQVKIWFQNHRYKTKRAQNEKG 608
            ....|:...||:.||..:.||.||||:||||.|.|.||.|.|.|
  Fly   323 EGNHYVVGAERKQLAQGLSLTETQVKVWFQNRRTKHKRMQQEGG 366

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vnd	NP_476786.2	Homeodomain	546..602	CDD:459649	25/56 (45%)
E5	NP_524825.1	Homeodomain	304..360	CDD:459649	25/55 (45%)