Protein Alignment vnd and MEOX2

DIOPT Version :10

• Sequence 1: NP_476786.2
• Gene: vnd / 31003
• FlyBaseID: FBgn0261930
• Length: 723
• Species: Drosophila melanogaster
• Sequence 2: NP_005915.2
• Gene: MEOX2 / 4223
• HGNCID: 7014
• Length: 304
• Species: Homo sapiens
• Alignment Length: 500
• Identity: 105/500 - (21%)
• Similarity: 141/500 - (28%)
• Gaps: 225/500 - (45%)

  Fly   226 HGSDLSHHSASESTSGHRGQGSHTSPSALS-----------PTPAGVSADEHHNGSGTGGGAGEA 279
            |.:....|..|:|:....|:..|.|...||           |...|:.|.:||.|
Human    13 HATAQGLHPFSQSSLALHGRSDHMSYPELSTSSSSCIIAGYPNEEGMFASQHHRG---------- 67

  Fly   280 DHHSTTEHHAPPSHPQQQHPHHQQHHHPHLLLPQQHHQQAVAPLPLAHHQSGEAQSH----AHAN 340
             ||    ||           ||..|||        ||||       ..||:.:...|    :...
Human    68 -HH----HH-----------HHHHHHH--------HHQQ-------QQHQALQTNWHLPQMSSPP 101

  Fly   341 AAAAHLLASHNAAAAAAVAAGQYLPNLPKNFPGSFGDEMSSYHHMAQTMLQHSGRSAWIKENELY 405
            :||.|.|...                     |.|.|
Human   102 SAARHSLCLQ---------------------PDSGG----------------------------- 116

  Fly   406 GTQQPASPDSTSPVTSEVSYTYIGSNCQTSPALS-GDYKSYSRSADSDALSVGDALHTLHGSSGN 469
                |....|:.||....| :.:||:..|..|.: ||   |.|.|.|.|
Human   117 ----PPELGSSPPVLCSNS-SSLGSSTPTGAACAPGD---YGRQALSPA---------------- 157

  Fly   470 GSAGGAPTAHALHNNNNNTTNNNNHSLKAEGINGAGSGHDDSLNEDGIEEDIDDVDDADGSGGGD 534
                                       :||..:|.....|.|             |..:|:...:
Human   158 ---------------------------EAEKRSGGKRKSDSS-------------DSQEGNYKSE 182

  Fly   535 ANGSDGLPNKKRKRRVLFTKAQTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHRYK 599
            .|      :|.||.|..|||.|..|||..|....||:...|..:|..:.||..|||:||||.|.|
Human   183 VN------SKPRKERTAFTKEQIRELEAEFAHHNYLTRLRRYEIAVNLDLTERQVKVWFQNRRMK 241

  Fly   600 TKRAQNEKGYEGHPGLLHGHATHPHHPSALPSPRRVAVPVLVRNGKPCLGDSSKLGADCVSVSSA 664
            .||.:.  |.:|                                       ::....:.|:|...
Human   242 WKRVKG--GQQG---------------------------------------AAAREKELVNVKKG 265

  Fly   665 TATAMQNAAAHHLVALNGAAAYQHAAAAAAGLHAHAHAHAHAHGH 709
            |....:.:..       |||..|....:.|...:|...|:..|.|
Human   266 TLLPSELSGI-------GAATLQQTGDSIANEDSHDSDHSSEHAH 303

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vnd	NP_476786.2	Homeodomain	546..602	CDD:459649	26/55 (47%)
MEOX2	NP_005915.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	63..192		53/289 (18%)
		COG5576	160..284	CDD:227863	45/190 (24%)
		Homeodomain	188..244	CDD:459649	26/55 (47%)