Protein Alignment vnd and MEOX1

DIOPT Version :10

• Sequence 1: NP_476786.2
• Gene: vnd / 31003
• FlyBaseID: FBgn0261930
• Length: 723
• Species: Drosophila melanogaster
• Sequence 2: NP_004518.1
• Gene: MEOX1 / 4222
• HGNCID: 7013
• Length: 254
• Species: Homo sapiens
• Alignment Length: 396
• Identity: 85/396 - (21%)
• Similarity: 122/396 - (30%)
• Gaps: 161/396 - (40%)

  Fly   251 PSALS-------PTPA-GVSADEHHNGSGTGGGAGEADHHSTTEHHAPPSHPQQQHPHHQQHHHP 307
            |:|.|       |.|. |...:.|..|:|..|              .|              |:|
Human     3 PAASSCMRSLQPPAPVWGCLRNPHSEGNGASG--------------LP--------------HYP 39

  Fly   308 HLLLPQQHHQQAVAPLPLAHHQSGEAQSHAHANAAAAHLLASHNAA----AAAAVAAGQYLPNLP 368
                          |.|.:.||..:             .||:..||    :|:.:||      .|
Human    40 --------------PTPFSFHQKPD-------------FLATATAAYPDFSASCLAA------TP 71

  Fly   369 KNFPGSFGDEMSSYHHMAQTMLQHSGRSAWIKENELYGTQQPASPDSTS---PVTSEVSYTYIGS 430
            .:.|                           :|..::..|.||.|.|.:   ||          |
Human    72 HSLP---------------------------QEEHIFTEQHPAFPQSPNWHFPV----------S 99

  Fly   431 NCQTSPALSGDYKSYSRSADSDALSVGDALHTLHGSSGNGSAGGAPTAHALHNNNNNTTNNNNHS 495
            :.:..|                               .:|.|||:...........:||......
Human   100 DARRRP-------------------------------NSGPAGGSKEMGTSSLGLVDTTGGPGDD 133

  Fly   496 LKAEGINGAGSGHDDSLNEDGIEEDIDDVDDADGSGGGDANGSDGLPNKKRKRRVLFTKAQTYEL 560
            .   |:.|:.:...:..:....:|..|:.::.     |...||    :|.||.|..|||.|..||
Human   134 Y---GVLGSTANETEKKSSRRRKESSDNQENR-----GKPEGS----SKARKERTAFTKEQLREL 186

  Fly   561 ERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHRYKTKRAQNEKGYEGHPGLLHGHATHPHH 625
            |..|....||:...|..:|..:.|:..|||:||||.|.|.||.   ||  |.|...:|.......
Human   187 EAEFAHHNYLTRLRRYEIAVNLDLSERQVKVWFQNRRMKWKRV---KG--GQPISPNGQDPEDGD 246

  Fly   626 PSALPS 631
            .:|.||
Human   247 STASPS 252

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vnd	NP_476786.2	Homeodomain	546..602	CDD:459649	25/55 (45%)
MEOX1	NP_004518.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	86..178		25/144 (17%)
		Homeodomain	172..228	CDD:459649	25/55 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	227..254		10/31 (32%)